Silencer (DNA)
Encyclopedia
In genetics
a silencer is a DNA
sequence capable of binding transcription regulation factors termed repressor
s. Upon binding, RNA polymerase
is prevented from initiating transcription
thus decreasing or fully suppressing RNA
synthesis.
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....
a silencer is a DNA
DNA
Deoxyribonucleic acid is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms . The DNA segments that carry this genetic information are called genes, but other DNA sequences have structural purposes, or are involved in...
sequence capable of binding transcription regulation factors termed repressor
Repressor
In molecular genetics, a repressor is a DNA-binding protein that regulates the expression of one or more genes by binding to the operator and blocking the attachment of RNA polymerase to the promoter, thus preventing transcription of the genes. This blocking of expression is called...
s. Upon binding, RNA polymerase
RNA polymerase
RNA polymerase is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses...
is prevented from initiating transcription
Transcription (genetics)
Transcription is the process of creating a complementary RNA copy of a sequence of DNA. Both RNA and DNA are nucleic acids, which use base pairs of nucleotides as a complementary language that can be converted back and forth from DNA to RNA by the action of the correct enzymes...
thus decreasing or fully suppressing RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
synthesis.