Sisters is a 2006

2006 in film

- Highest-grossing films :Please note that following the tradition of the English-language film industry, these are the top-grossing films that were first released in the United States in 2006...

 independent

Independent film

An independent film, or indie film, is a professional film production resulting in a feature film that is produced mostly or completely outside of the major film studio system. In addition to being produced and distributed by independent entertainment companies, independent films are also produced...

 horror film

Horror film

Horror films seek to elicit a negative emotional reaction from viewers by playing on the audience's most primal fears. They often feature scenes that startle the viewer through the means of macabre and the supernatural, thus frequently overlapping with the fantasy and science fiction genres...

 directed by Douglas Buck

Douglas Buck

Douglas Buck is an American film director.Buck grew up in Long Island, later moving to New York City, where he began making films while working as an airport electrical engineer. Buck started by making short films, including Cutting Moments , Home , and Prologue , all three of which were collected...

. It is a remake

Remake

A remake is a piece of media based primarily on an earlier work of the same medium.-Film:The term "remake" is generally used in reference to a movie which uses an earlier movie as the main source material, rather than in reference to a second, later movie based on the same source...

 of the 1973 Brian De Palma

Brian De Palma

Brian Russell De Palma is an American film director and writer. In a career spanning over 40 years, he is probably best known for his suspense and crime thriller films, including such box office successes as the horror film Carrie, Dressed to Kill, Scarface, The Untouchables, and Mission:...

 film of the same name. The film stars Stephen Rea

Stephen Rea

Stephen Rea is an Irish film and stage actor. Rea has appeared in high profile films such as V for Vendetta, Michael Collins, Interview with the Vampire and Breakfast on Pluto...

, Lou Doillon

Lou Doillon

Lou Doillon is a French model and actress. Her father is director Jacques Doillon and her mother is British actress and singer Jane Birkin.-Biography:...

, and Chloë Sevigny

Chloë Sevigny

Chloë Stevens Sevigny is an American film actress, fashion designer and former model. Sevigny gained reputation for her eclectic fashion sense and developed a broad career in the fashion industry in the mid 1990s, both for modeling and for her work at New York's Sassy magazine, which labeled her...

 in the leading roles, with Dallas Roberts

Dallas Roberts

Dallas Mark Roberts is an American stage and screen actor.Roberts was born in Houston, Texas. He is a graduate of Juilliard School. He is primarily based in New York City, where he regularly appears in theatrical productions...

 and JR Bourne playing supporting characters. The story centers on a news reporter (Sevigny) who, after witnessing a murder, becomes involved in a crime investigation surrounding a mysterious doctor (Rea) and one of his former patients, a young French

French people

The French are a nation that share a common French culture and speak the French language as a mother tongue. Historically, the French population are descended from peoples of Celtic, Latin and Germanic origin, and are today a mixture of several ethnic groups...

 woman who was born with a Siamese twin.

The movie was filmed in 2006 in North Carolina

North Carolina

North Carolina is a state located in the southeastern United States. The state borders South Carolina and Georgia to the south, Tennessee to the west and Virginia to the north. North Carolina contains 100 counties. Its capital is Raleigh, and its largest city is Charlotte...

 as well as Vancouver, British Columbia on an estimated budget of $60,000. The film had a troubled release history, and was never given a theatrical release; it was eventually released on DVD

DVD

A DVD is an optical disc storage media format, invented and developed by Philips, Sony, Toshiba, and Panasonic in 1995. DVDs offer higher storage capacity than Compact Discs while having the same dimensions....

 in the United States on March 11, 2008.

Cast

Stephen Rea

Stephen Rea

Stephen Rea is an Irish film and stage actor. Rea has appeared in high profile films such as V for Vendetta, Michael Collins, Interview with the Vampire and Breakfast on Pluto...

 as Dr. Philip Lacan

Lou Doillon

Lou Doillon

Lou Doillon is a French model and actress. Her father is director Jacques Doillon and her mother is British actress and singer Jane Birkin.-Biography:...

 as Angelique/Annabel Tristiana

Chloë Sevigny

Chloë Sevigny

Chloë Stevens Sevigny is an American film actress, fashion designer and former model. Sevigny gained reputation for her eclectic fashion sense and developed a broad career in the fashion industry in the mid 1990s, both for modeling and for her work at New York's Sassy magazine, which labeled her...

 as Grace Collier

Dallas Roberts

Dallas Roberts

Dallas Mark Roberts is an American stage and screen actor.Roberts was born in Houston, Texas. He is a graduate of Juilliard School. He is primarily based in New York City, where he regularly appears in theatrical productions...

 as Dylan Wallace

JR Bourne as Larry Franklin

William B. Davis

William B. Davis

William Bruce Davis is a Canadian actor, known for his role as The Smoking Man on The X-Files. He has also appeared in Stargate SG-1 as Damaris, a Prior of the Ori and as Mayor Tate on Smallville...

 as Dr. Bryant

Gabrielle Rose

Gabrielle Rose (actress)

Gabrielle Rose is an accomplished Canadian actress. She has an extensive resume that includes multiple nominations for Genie Awards and Gemini Awards...

 as Dr. Mercedes Kent

Talia Williams as Lily

Rachel Williams

Rachel Williams

Rachel Williams is an American model, actress, and TV presenter now living in the United Kingdom.- Biography :Her father Tod Williams and stepmother Billie Tsien are architects in the Manhattan firm Tod Williams Billie Tsien Architects, well known for their American Folk Art Museum, which many...

as Eve

Erica Van Briel as Sofia Tristiana