Skene's gland
Encyclopedia
In human anatomy
Human anatomy
Human anatomy is primarily the scientific study of the morphology of the human body. Anatomy is subdivided into gross anatomy and microscopic anatomy. Gross anatomy is the study of anatomical structures that can be seen by the naked eye...

 (female), the Skene's glands (also known as the lesser vestibular glands, periurethral glands, skene glands, paraurethral glands, female prostate
Prostate
The prostate is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals....

) are glands located on the anterior wall of the vagina
Vagina
The vagina is a fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles. Female insects and other invertebrates also have a vagina, which is the terminal part of the...

, around the lower end of the urethra
Urethra
In anatomy, the urethra is a tube that connects the urinary bladder to the genitals for the removal of fluids out of the body. In males, the urethra travels through the penis, and carries semen as well as urine...

. They drain into the urethra and near the urethral opening and may be near or a part of the G-Spot
G-spot
The Gräfenberg Spot, often called the G-Spot, is a bean-shaped area of the vagina. Many women report that it is an erogenous zone which, when stimulated, can lead to strong sexual arousal, powerful orgasms and female ejaculation...

. These glands are surrounded with tissue, which includes the part of the clitoris
Clitoris
The clitoris is a sexual organ that is present only in female mammals. In humans, the visible button-like portion is located near the anterior junction of the labia minora, above the opening of the urethra and vagina. Unlike the penis, which is homologous to the clitoris, the clitoris does not...

 that reaches up inside the vagina and swells with blood
Blood
Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells....

 during sexual arousal
Sexual arousal
Sexual arousal, or sexual excitement, is the arousal of sexual desire, during or in anticipation of sexual activity. Things that precipitate human sexual arousal are called erotic stimuli, or colloquially known as turn-ons. There are many potential stimuli, both physical or mental, which can cause...

.

Female ejaculation

The location of the Skene's gland is the general area of the vulva
Vulva
The vulva consists of the external genital organs of the female mammal. This article deals with the vulva of the human being, although the structures are similar for other mammals....

, glands located on the anterior wall of the vagina around the lower end of the urethra
Urethra
In anatomy, the urethra is a tube that connects the urinary bladder to the genitals for the removal of fluids out of the body. In males, the urethra travels through the penis, and carries semen as well as urine...

. It has been postulated that the Skene's glands are the source of female ejaculation
Female ejaculation
Female ejaculation refers to the expulsion of noticeable amounts of clear fluid by human females from the paraurethral ducts through and around the urethra during or before an orgasm...

. In 2002, Emanuele Jannini of L'Aquila University in Italy showed that there may be an explanation both for the phenomenon and for the frequent denials of its existence. Skene's glands have highly variable anatomy, and in some extreme cases they appear to be absent entirely. If Skene's glands are the cause of female ejaculation and G-Spot
G-spot
The Gräfenberg Spot, often called the G-Spot, is a bean-shaped area of the vagina. Many women report that it is an erogenous zone which, when stimulated, can lead to strong sexual arousal, powerful orgasms and female ejaculation...

-orgasms, this may explain the absence in many women.

It has been demonstrated that a large amount of lubricating fluid (filtered blood plasma) can be secreted from this gland when stimulated from inside the vagina. Some reports indicate that embarrassment regarding female ejaculation, and the mistaken notion that the substance is urine, can lead to purposeful suppression of sexual climax, leading women to seek medical advice and even undergo surgery to "stop the urine".

Female prostate

The Skene's glands are homologous
Homology (biology)
Homology forms the basis of organization for comparative biology. In 1843, Richard Owen defined homology as "the same organ in different animals under every variety of form and function". Organs as different as a bat's wing, a seal's flipper, a cat's paw and a human hand have a common underlying...

 with the prostate
Prostate
The prostate is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals....

 gland in males. The fluid that emerges during sex, female ejaculation
Female ejaculation
Female ejaculation refers to the expulsion of noticeable amounts of clear fluid by human females from the paraurethral ducts through and around the urethra during or before an orgasm...

, has a composition somewhat similar to the fluid generated in males by the prostate gland, containing biochemical markers of sexual function like human urinary protein 1 and the enzyme PDE5
CGMP specific phosphodiesterase type 5
cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum and the retina....

 where women without the gland had lower concentrations. When examined with electron microscopy, both glands show similar secretory structures, and both act similarly in terms of prostate-specific antigen and prostate-specific acid phosphatase
Acid phosphatase
Acid phosphatase is a phosphatase, a type of enzyme, used to free attached phosphate groups from other molecules during digestion. It is basically a phosphomonoesterase...

 studies. Because they are increasingly perceived as merely different versions of the same gland, some researchers are moving away from the name Skene's gland and are referring to it instead as the female prostate.

Eponym

The glands were named after the physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

 who described them first in Western medical literature, Alexander Skene
Alexander Skene
Alexander Johnston Chalmers Skene was a British gynaecologist who described what became known as the Skene's glands.-Biography:...

.

Disorders

Disorders of or related to the Skene's gland include:
  • Infection (skenitis)
  • Skene's duct cyst

See also

  • Bartholin's gland
    Bartholin's gland
    The Bartholin's glands are two glands located slightly posterior and to the left and right of the opening of the vagina. They secrete mucus to lubricate the vagina and are homologous to bulbourethral glands in males...

  • List of homologues of the human reproductive system
  • Pudendal nerve
    Pudendal nerve
    The pudendal nerve is a sensory and somatic nerve in the pelvic region which is a large branch of the sacral plexus that innervates the external genitalia of both sexes, as well as sphincters for the bladder and the rectum...

  • Vaginal orgasm
  • Wolffian duct
    Wolffian duct
    The mesonephric duct is a paired organ found in mammals including humans during embryogenesis....

  • Vaginal lubrication
    Vaginal lubrication
    Vaginal lubrication is a lubricating fluid that is naturally produced in a woman's vagina. Vaginal lubrication or moistness is present at all times, but production increases significantly during a woman's sexual arousal in anticipation of sexual intercourse...


External links




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