Skin and skin structure infection
Encyclopedia
A skin and skin structure infection (SSSI) is a bacteria
l infection of skin and associated tissues. It often requires treatment by antibiotics.
It is/was divided into two types, complicated skin and skin structure infection (cSSSI) and
uncomplicated skin and skin structure infection (uSSSI).
The U.S. Food and Drug Administration (FDA) defined these as:
The two categories had different regulatory approval requirements.
The uncomplicated category normally only involve Staphylococcus aureus
and Streptococcus pyogenes
.
Bacteria
Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...
l infection of skin and associated tissues. It often requires treatment by antibiotics.
It is/was divided into two types, complicated skin and skin structure infection (cSSSI) and
uncomplicated skin and skin structure infection (uSSSI).
The U.S. Food and Drug Administration (FDA) defined these as:
The two categories had different regulatory approval requirements.
The uncomplicated category normally only involve Staphylococcus aureus
Staphylococcus aureus
Staphylococcus aureus is a facultative anaerobic Gram-positive coccal bacterium. It is frequently found as part of the normal skin flora on the skin and nasal passages. It is estimated that 20% of the human population are long-term carriers of S. aureus. S. aureus is the most common species of...
and Streptococcus pyogenes
Streptococcus pyogenes
Streptococcus pyogenes is a spherical, Gram-positive bacterium that is the cause of group A streptococcal infections. S. pyogenes displays streptococcal group A antigen on its cell wall. S...
.