State Road 16 runs from northwest to southeast between Raiford

Raiford, Florida

Raiford is a town in Union County, Florida, United States. The population was 187 at the 2000 census. As of 2004, the population recorded by the U.S...

 and St. Augustine

St. Augustine, Florida

St. Augustine is a city in the northeast section of Florida and the county seat of St. Johns County, Florida, United States. Founded in 1565 by Spanish explorer and admiral Pedro Menéndez de Avilés, it is the oldest continuously occupied European-established city and port in the continental United...

. It passes through the towns of Starke

Starke, Florida

Starke is a city in Bradford County, Florida, United States. The population was 5,593 at the 2000 census. As of 2004, the population recorded by the U.S. Census Bureau is 5,769 ....

 and Green Cove Springs

Green Cove Springs, Florida

Green Cove Springs is a city in Clay County, Florida, United States. The population was 5,378 at the 2000 census. As of 2010, the population recorded by the U.S. Census Bureau is 6,908. It is the county seat of Clay County....

 in addition to providing access to Camp Blanding

Camp Blanding

Camp Blanding Joint Training Center is the primary military reservation and training base for the Florida National Guard, both the Florida Army National Guard and certain non-flying activities of the Florida Air National Guard. The installation is located in Clay County, Florida near the city of...

.

SR 16 crosses the St. Johns River using the Shands Bridge

Shands Bridge

The Shands Bridge is a highway bridge over the St. Johns River near Jacksonville, Florida. The span was first opened in 1929. It was located just north of the current span, crossing from Orangedale to the present Shands pier on the west side of the river....

. This bridge connects Clay and St. Johns Counties. The Shands is often considered an emergency alternative to the Buckman Bridge that is farther north. The difference between both bridges is that the Buckman, which carries Interstate 295, has eight lanes in each direction while the Shands has only two lanes.

Major roads and/or highways that SR 16 crosses include: US 1

U.S. Route 1 in Florida

U.S. Route 1 in Florida runs along the state's east coast from Key West to its crossing of the St. Marys River into Georgia north of Boulogne, and south of Folkston. US 1 was designated through Florida when the U.S. Highway System was established in 1926.US 1 runs in the state of Florida, and...

, Interstate 95, SR 13, US 17

U.S. Route 17 in Florida

U.S. Route 17 in Florida is a north–south United States Highway. It runs from the Punta Gorda, Florida Metropolitan Statistical Area northeast to the Greater Jacksonville Metropolitan Area....

, SR 21 and US 301

U.S. Route 301 in Florida

U.S. Route 301 in Florida runs from the Sarasota-Bradenton-Venice, Florida Metropolitan Statistical Area northeast to the Greater Jacksonville Metropolitan Area. The road is a spur of U.S...

.

Junction list

{|class="wikitable"
!County
!Location
!Mile
!Destinations
!Notes
|-
|Union

Union County, Florida

Union County is a county located in the state of Florida. The U.S. Census Bureau 2005 estimate for the county was 14,916. The county seat is Lake Butler.- History :...

|Raiford

Raiford, Florida

Raiford is a town in Union County, Florida, United States. The population was 187 at the 2000 census. As of 2004, the population recorded by the U.S...

|0.00
|
|Western terminus
|-
|Bradford

Bradford County, Florida

Bradford County is a county located in the U.S. state of Florida. As of 2000, the population was 26,088. The 2005 U.S. Census Bureau estimate for the county was 28,118 . Its county seat is Starke, Florida. Bradford County is the home of the Florida State Prison as well as several other state...

|Starke

Starke, Florida

Starke is a city in Bradford County, Florida, United States. The population was 5,593 at the 2000 census. As of 2004, the population recorded by the U.S. Census Bureau is 5,769 ....

|
|
|
|-
|rowspan=3|Clay

Clay County, Florida

Clay County is a county located in the U.S. state of Florida. As of 2010, the population was 190,895. Its county seat is Green Cove Springs, Florida. Clay County is part of the Greater Jacksonville Metropolitan area.- History :...

|Camp Blanding
|
|
|
|-
|
|
|
|
|-
|Green Cove Springs

Green Cove Springs, Florida

Green Cove Springs is a city in Clay County, Florida, United States. The population was 5,378 at the 2000 census. As of 2010, the population recorded by the U.S. Census Bureau is 6,908. It is the county seat of Clay County....

|
|
|Brief concurrency
|-
|colspan=2 align=center|St. Johns River

St. Johns River

The St. Johns River is the longest river in the U.S. state of Florida and its most significant for commercial and recreational use. At long, it winds through or borders twelve counties, three of which are the state's largest. The drop in elevation from the headwaters to the mouth is less than ;...

|
|colspan=2 align=center|Shands Bridge

Shands Bridge

The Shands Bridge is a highway bridge over the St. Johns River near Jacksonville, Florida. The span was first opened in 1929. It was located just north of the current span, crossing from Orangedale to the present Shands pier on the west side of the river....

|-
|rowspan=4|St. Johns

St. Johns County, Florida

St. Johns County is a county located in northeastern Florida. As of the 2010 census, the population was 190,039. The county seat is St. Augustine. Due to the inclusion of Ponte Vedra Beach, it is one of the highest-income counties in the United States....

|Orangedale
|
|
|
|-
|
|
|
|
|-
|rowspan=2|St. Augustine

St. Augustine, Florida

St. Augustine is a city in the northeast section of Florida and the county seat of St. Johns County, Florida, United States. Founded in 1565 by Spanish explorer and admiral Pedro Menéndez de Avilés, it is the oldest continuously occupied European-established city and port in the continental United...

|63.5
|
|
|-
|63.6
|
|Eastern terminus

Related route

CR 16A is a county road in St. Johns County, Florida

St. Johns County, Florida

St. Johns County is a county located in northeastern Florida. As of the 2010 census, the population was 190,039. The county seat is St. Augustine. Due to the inclusion of Ponte Vedra Beach, it is one of the highest-income counties in the United States....

. It is a spur of SR 16 in northwestern St. Johns. It goes through mainly rural land. It begins at SR 13 just north of the Shands Bridge

Shands Bridge

The Shands Bridge is a highway bridge over the St. Johns River near Jacksonville, Florida. The span was first opened in 1929. It was located just north of the current span, crossing from Orangedale to the present Shands pier on the west side of the river....

 and continues about 1.5 miles before making a junction with County Road 210 after wards it continues till its end at SR 16 near World Golf Village

World Golf Village

The World Golf Village is a golf resort located midway between Jacksonville and St. Augustine, Florida, built to showcase the World Golf Hall of Fame and intended to be the ultimate golf destination for players and fans of the game.-Development:...

.