State Route 388 is a short highway that runs north-to-south from S.R. 232 in the community of Lewiston, USA, in the north to S.R. 223 in Grovetown

Grovetown, Georgia

Grovetown, Georgia is a city in Columbia County, in the United States state of Georgia. It is part of the Augusta, Georgia metropolitan area as well as the Central Savannah River Area. As of the 2010 census, the city had a population of 11,216. The mayor of Grovetown is George W...

 in the south, along Lewistown Road, Horizon South Parkway, and Wrightsboro Road. The route has an interchange with Interstate 20

Interstate 20

Interstate 20 is a major east–west Interstate Highway in the Southern United States. I‑20 runs 1,535 miles from near Kent, Texas, at Interstate 10 to Florence, South Carolina, at Interstate 95...

 near its midpoint, and the route serves to connect S.R. 232 and S.R. 223, which run parallel to each other on opposite sides of Interstate 20 in southern Columbia County

Columbia County, Georgia

Columbia County is a county located in the US state of Georgia along the Savannah River. As of 2010 the population was 124,054 a growth of 39% from the 2000 census figure of 89,288. The de jure county seat is Appling. Appling is an unincorporated area, making Columbia one of only three counties...

.