Subepithelial mucinous corneal dystrophy
Encyclopedia
Subepithelial mucinous corneal dystrophy (SMCD) is a rare form of human corneal dystrophy
. It was first described in 1993 by Feder et al. Anterior to Bowman layer, deposits of glycosaminoglycan
were detected and identified as chondroitin-4-sulfate
and dermatan sulfate
.
Corneal dystrophy (human)
Human corneal dystrophy is a group of disorders, characterised by a noninflammatory, inherited, bilateral opacity of the transparent front part of the human eye called the cornea...
. It was first described in 1993 by Feder et al. Anterior to Bowman layer, deposits of glycosaminoglycan
Glycosaminoglycan
Glycosaminoglycans or mucopolysaccharides are long unbranched polysaccharides consisting of a repeating disaccharide unit. The repeating unit consists of a hexose or a hexuronic acid, linked to a hexosamine .-Production:Protein cores made in the rough endoplasmic reticulum are posttranslationally...
were detected and identified as chondroitin-4-sulfate
Chondroitin sulfate
Chondroitin sulfate is a sulfated glycosaminoglycan composed of a chain of alternating sugars . It is usually found attached to proteins as part of a proteoglycan. A chondroitin chain can have over 100 individual sugars, each of which can be sulfated in variable positions and quantities...
and dermatan sulfate
Dermatan sulfate
Dermatan sulfate is a glycosaminoglycan found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs....
.