Tegumental Angiomyxoma-Neurothekeoma (TAN syndrome) a syndrome

Syndrome

In medicine and psychology, a syndrome is the association of several clinically recognizable features, signs , symptoms , phenomena or characteristics that often occur together, so that the presence of one or more features alerts the physician to the possible presence of the others...

, an acronym, and eponym

Eponym

An eponym is the name of a person or thing, whether real or fictitious, after which a particular place, tribe, era, discovery, or other item is named or thought to be named...

proposed by the ophthalmologist, Tan Aik Kah. Angiomyxomas are associated with LAMB

Carney complex

Carney complex, also known as LAMB syndrome and NAME syndrome is an autosomal dominant condition comprising myxomas of the heart and skin, hyperpigmentation of the skin , and endocrine overactivity It is distinct from Carney's triad...

 (lentigines, atrial myxomas, muco-cutaneous myxomas, and blue naevi) syndrome, NAME (nevi, atrial myxoma, myxoid neurofibromas, and ephelides) syndrome and Carney syndrome

Carney complex

Carney complex, also known as LAMB syndrome and NAME syndrome is an autosomal dominant condition comprising myxomas of the heart and skin, hyperpigmentation of the skin , and endocrine overactivity It is distinct from Carney's triad...

 (atrial, cutaneous and mammary myxomas, lentigines, blue naevi, endocrine disorders and testicular tumours).

TAN syndrome is characterized by multiple superficial angiomyxoma

Angiomyxoma

Angiomyxoma is a myxomatous tumor involving the blood vessels.It can affect the vulva and other parts of the pelvis.Aggressive angiomyxoma was originally described in 1983, but the term "angiomyxoma" dates back to at least 1952....

 and neurothekeoma

Neurothekeoma

Neurothekeoma is a Myxoma and is composed of cords and nests of large cells packed among collagen bundles in close proximity to small nerves....

confined only to the skin (tegument). TAN syndrome may be used to describe myxomas confined to the skin without visceral involvement.

Case

Tan et al.[1] reported a 10 year old girl with multiple superficial angiomyxoma associated with neurothekeoma palpebrae. The was no evidence of visceral involvement. The lesions were excised with no recurrence during followup.