TRAF1
Encyclopedia
TNF receptor-associated factor 1 is a protein
that in humans is encoded by the TRAF1 gene
.
with CD30
, CFLAR
, Baculoviral IAP repeat-containing protein 3
, BIRC2
, Caspase 8
, HIVEP3
, TNFAIP3
, TRAF2
, RANK
and TRAF interacting protein
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the TRAF1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
TRAF1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with CD30
CD30
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker.This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the...
, CFLAR
CFLAR
CASP8 and FADD-like apoptosis regulator is a protein that in humans is encoded by the CFLAR gene. Also called FLICE-like inhibitory protein .-Further reading:...
, Baculoviral IAP repeat-containing protein 3
Baculoviral IAP repeat-containing protein 3
Baculoviral IAP repeat-containing protein 3 is a protein that in humans is encoded by the BIRC3 gene.-Interactions:...
, BIRC2
BIRC2
Baculoviral IAP repeat-containing protein 2 is a protein that in humans is encoded by the BIRC2 gene.-Interactions:...
, Caspase 8
Caspase 8
Caspase 8 is a caspase protein, encoded by the CASP8 gene. It most likely acts upon caspase 3.CASP8 orthologs have been identified in numerous mammals for which complete genome data are available...
, HIVEP3
HIVEP3
Transcription factor HIVEP3 is a protein that in humans is encoded by the HIVEP3 gene.-Interactions:HIVEP3 has been shown to interact with TRAF1 and TRAF2....
, TNFAIP3
TNFAIP3
Tumor necrosis factor, alpha-induced protein 3 is a protein that in humans is encoded by the TNFAIP3 gene.-Interactions:TNFAIP3 has been shown to interact with TNIP1, TRAF1, TRAF2, IKBKG, TAX1BP1, YWHAB, YWHAZ, TRAF6 and YWHAH....
, TRAF2
TRAF2
TNF receptor-associated factor 2 is a protein that in humans is encoded by the TRAF2 gene.-Interactions:TRAF2 has been shown to interact with BCL10, CD30, CFLAR, IKK2, MAP3K7IP2, CD137, Caveolin 1, CD27, TNFRSF13B, TANK-binding kinase 1, TRAF1, CD40, UBE2N, MAP3K14, MAP4K2, CASP8AP2, HIVEP3,...
, RANK
RANK
Receptor Activator of Nuclear Factor κ B , also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding...
and TRAF interacting protein
TRAF interacting protein
TRAF-interacting protein is a protein that in humans is encoded by the TRAIP gene.-Interactions:TRAF interacting protein has been shown to interact with FLII, TRAF1 and TRAF2.-Further reading:...
.