TRAF6
Encyclopedia
TRAF6 is a TRAF
human protein.
with SDCBP
, IRAK2
, IRAK1
, MAP3K7IP2
, MAP3K7IP1
, TNFRSF13B
, FHL2
, CD40
, IKBKG
, RANK
, HSPB2
, UBE2N
, SIGIRR
, TAX1BP1
, ASK1
, PPP4C
, TNFAIP3
, Sequestosome 1
, MAP3K7
and Ubiquitin C
.
TRAF
TNF receptor associated factors also known as TRAFs are a family of proteins primarily involved in the regulation of inflammation, antiviral responses and apoptosis....
human protein.
Interactions
TRAF6 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with SDCBP
SDCBP
Syntenin-1 is a protein that in humans is encoded by the SDCBP gene.-Interactions:SDCBP has been shown to interact with Merlin, ULK1, Interleukin 5 receptor alpha subunit, SOX4, RAB5A, EFNB1, TRAF6, GRIK1 and GRIK2.-Further reading:...
, IRAK2
IRAK2
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene.-Interactions:IRAK2 has been shown to interact with TRAF6 and Myd88.-Further reading:...
, IRAK1
IRAK1
Interleukin-1 receptor-associated kinase 1 is an enzyme that in humans is encoded by the IRAK1 gene.-Interactions:IRAK1 has been shown to interact with Myd88, IKBKG, IKK2, TRAF6, CHUK and Ubiquitin C.-Further reading:...
, MAP3K7IP2
MAP3K7IP2
Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 is an enzyme that in humans is encoded by the MAP3K7IP2 gene.The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK...
, MAP3K7IP1
MAP3K7IP1
Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 is an enzyme that in humans is encoded by the MAP3K7IP1 gene.This protein plays an important role in skin homeostasis, wound repair, and oncogenesis.-Interactions:...
, TNFRSF13B
TNFRSF13B
Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system....
, FHL2
FHL2
Four and a half LIM domains protein 2 is a protein that in humans is encoded by the FHL2 gene.-Interactions:FHL2 has been shown to interact with Beta-catenin, Titin, Zinc finger and BTB domain-containing protein 16, Integrin, beta 6, Androgen receptor, ITGA7, CREB1, MAPK1, CD49c, ZNF638, BRCA1,...
, CD40
CD40 (protein)
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects....
, IKBKG
IKBKG
NF-kappa-B essential modulator also known as inhibitor of nuclear factor kappa-B kinase subunit gamma is a protein that in humans is encoded by the IKBKG gene. NEMO is a subunit of the IκB kinase that activates NF-κB. The human gene for IKBKG is located on chromosome Xq28...
, RANK
RANK
Receptor Activator of Nuclear Factor κ B , also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding...
, HSPB2
HSPB2
Heat shock protein beta-2 is a protein that in humans is encoded by the HSPB2 gene.-Interactions:HSPB2 has been shown to interact with TRAF6, HSPB8, Myotonic dystrophy protein kinase and CRYAB.-Further reading:...
, UBE2N
UBE2N
Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.-Interactions:UBE2N has been shown to interact with Aurora A kinase, TRAF2, TRAF6, HLTF and UBE2V1.-Further reading:...
, SIGIRR
SIGIRR
Single Ig IL-1-related receptor is a protein that in humans is encoded by the SIGIRR gene.-Further reading:...
, TAX1BP1
TAX1BP1
Tax1-binding protein 1 is a protein that in humans is encoded by the TAX1BP1 gene.-Interactions:TAX1BP1 has been shown to interact with TNFAIP3 and TRAF6.TAX1BP1 binds to TNFAIP3 or TRAF6 and suppresses to NF-kappaB transcriptional activation....
, ASK1
ASK1
Apoptosis signal-regulating kinase 1 also known as mitogen-activated protein kinase kinase kinase 5 is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway...
, PPP4C
PPP4C
Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the PPP4C gene.-Interactions:PPP4C has been shown to interact with CCT2, CCT4, CCT7, SMEK2, CCT6A, CCT3, IGBP1, PPP4R1, CCT5, T-complex 1, REL, CCDC6, TRAF6 and PPP2R1A.-Further reading:...
, TNFAIP3
TNFAIP3
Tumor necrosis factor, alpha-induced protein 3 is a protein that in humans is encoded by the TNFAIP3 gene.-Interactions:TNFAIP3 has been shown to interact with TNIP1, TRAF1, TRAF2, IKBKG, TAX1BP1, YWHAB, YWHAZ, TRAF6 and YWHAH....
, Sequestosome 1
Sequestosome 1
Sequestosome-1 is a protein that in humans is encoded by the SQSTM1 gene.-Interactions:Sequestosome 1 has been shown to interact with RAD23A, TrkA, TrkB, PRKCI, RIPK1, TRAF6 and MAP1LC3A.-Further reading:...
, MAP3K7
MAP3K7
Mitogen-activated protein kinase kinase kinase 7 is an enzyme that in humans is encoded by the MAP3K7 gene.-Interactions:MAP3K7 has been shown to interact with Mothers against decapentaplegic homolog 6, MAP3K7IP2, MAP3K7IP1, MAP3K7IP3, ASK1, PPM1B, TRAF6, MAP2K6 and CHUK.-Further reading:...
and Ubiquitin C
Ubiquitin C
Ubiquitin is a protein that in humans is encoded by the UBC gene.-Interactions:Ubiquitin C has been shown to interact with SCNN1A, SCNN1G, Parkin , P70-S6 Kinase 1, TRAF6, HDAC3, SFPQ, S100A10, Mothers against decapentaplegic homolog 3, NOTCH1, HIF1A, Epidermal growth factor receptor, E2F1,...
.