Tachykinin receptor 2
Overview
 
Substance-K receptor is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the TACR2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

.
Several selective ligands for NK2 are now available, and although most of the compounds developed so far are peptides, one small-molecule antagonist Saredutant is currently in clinical trials as an anxiolytic
Anxiolytic
An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...

 and antidepressant
Antidepressant
An antidepressant is a psychiatric medication used to alleviate mood disorders, such as major depression and dysthymia and anxiety disorders such as social anxiety disorder. According to Gelder, Mayou &*Geddes people with a depressive illness will experience a therapeutic effect to their mood;...

.
  • GR-64349 - potent and selective agonist, EC50 3.7nM, 7-amino acid polypeptide chain.
Quotations

Only in America.

I can't believe that having said what I said was interpreted as having been what I said when I said it, because I said it where I said it, when I said it, and who I said it to.

I can't believe what I said about myself. What I said in my own private conversations with myself to an ESPN producer are my business, and I had no business saying them to someone else.

If a bullfrog had wings it wouldn't bump his behind every time he hopped.

Martin Luther King took us to the mountain top: I want to take us to the bank.

Thank god for money.

 
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