State Route 169 is a west-to-east secondary highway in Knox County

Knox County, Tennessee

Knox County is a county in the U.S. state of Tennessee. Its 2007 population was estimated at 423,874 by the United States Census Bureau. Its county seat is Knoxville, as it has been since the creation of the county. The county is at the geographical center of the Great Valley of East Tennessee...

 in the U.S. state

U.S. state

A U.S. state is any one of the 50 federated states of the United States of America that share sovereignty with the federal government. Because of this shared sovereignty, an American is a citizen both of the federal entity and of his or her state of domicile. Four states use the official title of...

 of Tennessee

Tennessee

Tennessee is a U.S. state located in the Southeastern United States. It has a population of 6,346,105, making it the nation's 17th-largest state by population, and covers , making it the 36th-largest by total land area...

.

The route is 11.7 miles (18.8 km) long. Its western terminus is in west Knox County at Tennessee State Route 131

Tennessee State Route 131

State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 67 miles long. It is designated as a secondary route.State Route 131 begins in Knoxville at Kingston Pike State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 67 miles (108 km)...

 (Lovell Road/Ball Camp-Byington Road). Its eastern terminus is in Knoxville

Knoxville, Tennessee

Founded in 1786, Knoxville is the third-largest city in the U.S. state of Tennessee, U.S.A., behind Memphis and Nashville, and is the county seat of Knox County. It is the largest city in East Tennessee, and the second-largest city in the Appalachia region...

 at Tennessee State Route 62

Tennessee State Route 62

State Route 62 is a west-to-east highway in the U.S. state of Tennessee that is 83 miles long. It is designated as a primary route.State Route 62 begins in Putnam County at State Route 84; it ends in Knox County at State Route 71....

 (Western Avenue). It is known as Middlebrook Pike for the entire length. Although SR-169 passes over I-640/I-75 and under I-40, there are no direct exits with either interstate highway.

After a section from Cedar Bluff Road to Tennessee State Route 131

Tennessee State Route 131

State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 67 miles long. It is designated as a secondary route.State Route 131 begins in Knoxville at Kingston Pike State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 67 miles (108 km)...

 (Lovell Road) was completed in 2007, the entire length is now four lanes. The majority of the roadway is a median divided highway.

Major intersections

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|0.0
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|Ball Camp-Byington Road continues west of intersection, Lovell Road south of the intersection
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|1.9
|Cedar Bluff Road
|TO
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|rowspan=9|Knoxville

Knoxville, Tennessee

Founded in 1786, Knoxville is the third-largest city in the U.S. state of Tennessee, U.S.A., behind Memphis and Nashville, and is the county seat of Knox County. It is the largest city in East Tennessee, and the second-largest city in the Appalachia region...

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|3.9
|Gallaher View Road (south)/Landmark Drive (north)
|TO
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|5.3
|Vanosdale Road (south)/Francis Road (north)
|TO
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|6.8
|Weisgarber Road
|TO
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!colspan=3|SR-169 westbound and eastbound separate for up to 0.2 mile (0.321868 km) from mile 7.4 to 8.5
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|8.9
|Ed Shouse Road
|TO SR-62 and
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|10.9
|Sutherland Avenue
|exit ramp from east
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|11.3
|Twenty First Street
|TO and
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|11.7
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