Therapeutic food
Encyclopedia
Therapeutic foods are food
Food
Food is any substance consumed to provide nutritional support for the body. It is usually of plant or animal origin, and contains essential nutrients, such as carbohydrates, fats, proteins, vitamins, or minerals...

s designed for specific, usually nutritional, therapeutic purposes as a form of dietary supplement
Dietary supplement
A dietary supplement, also known as food supplement or nutritional supplement, is a preparation intended to supplement the diet and provide nutrients, such as vitamins, minerals, fiber, fatty acids, or amino acids, that may be missing or may not be consumed in sufficient quantities in a person's diet...

. The primary examples of therapeutic foods are used for emergency feeding of malnourished children or to supplement the diets of persons with special nutritional requirements, such as the elderly.
Therapeutic foods are usually made of a mixture of protein, carbohydrate, lipid and vitamins and minerals. Therapeutic foods are usually produced by grinding all ingredients together and mixing the ingredients together. “The mixing process allows for the protein and carbohydrate components of the food to be embedded in the lipid matrix . The size of the particles within the mixture has to be less than 200 µm . , in order for the mixture to maintain its consistency. Using this method, the therapeutic food is produced and packaged without using water, which would eliminate the issue of spoilage of the food. Some therapeutic foods require the addition of water before administering, while others can be consumed as is. Therapeutic foods are designed and manufactured to ensure that the foods are ready to eat straight from the packaging. Those foods resist bacterial contamination and require no cooking .
The World Health Organization's standards for the treatment of malnutrition in children specify the use of two formulas during initial treatment, F-75 and F-100
F-100 (food)
F-100 and F-75 are therapeutic milk products designed to treat severe malnutrition. In 1994 Action Against Hunger / Action Contre la Faim pioneered the use of milk formula F-100 for the treatment of severe acute malnutrition...

. These formulas contain a mixture of powdered milk, sugar, and other ingredients designed to provide an easily absorbed mix of carbohydrates and essential micronutrients. They are generally provided as powdered mixes which are reconstituted with water. The WHO recommends the use of these formulas, with the gradual introduction of other foods, until the child approaches a normal weight.
The standard treatment of childhood malnutrition is administered in 2 phases . Phase one usually deals with children who are severely malnourished and very ill as a result. The therapy used in this phase is F-75, a milk-based liquid food containing modest amounts of energy and protein (75 kcal/100 mL and 0.9 g protein/100 mL) and the administration of parenteral antibiotics . When an improvement in the child’s appetite and clinical condition is observed, the child is then entered into phase two of the treatment. This phase uses F-100 for feeding the child. F-100 is a “specially formulated, high-energy, high-protein (100 kcal/100 mL, 2.9 g protein/100 mL) milk-based liquid food” . The child is in phase two until he/she is no longer wasted [weight-for-height z score (WHZ) 2] . Phase two starts while the child is at the hospital but is usually completed after the child goes home. The parent is then responsible for feeding the child a flour supplement made of cereal and legumes as a replacement for the milk-based foods used in phase one and phase two .

Ready-to-Use Therapeutic Food

A subset of therapeutic foods, ready-to-use therapeutic foods (RUTFs), are energy-dense, micronutrient-enriched pastes that have a nutritional profile similar to the traditional F-100 milk based diet used in inpatient therapeutic feeding programs and are often made of peanuts, oil, sugar and milk powder .
RUTFs are a “homogeneous mixture of lipid-rich and water-soluble foods” . The lipids used in formulating RUTFs are in a viscous liquid form. The other ingredients are in small particles and are mixed through the lipid. The other ingredients are protein, carbohydrate, vitamins and minerals. The mixture needs to be homogeneous in order for it to be effectively consumed, and to do this, a specific mixing process needs to be implemented . The fat/lipid component of the RUTF is heated and stirred first. The heat should be maintained in order for the lipid to remain in the most optimum form for mixing in the other ingredients. The protein, carbohydrate and vitamins and minerals are in a powdered format and are then slowly and gradually added to the lipid, while the lipid is being vigorously stirred. After all the ingredients are added to the liquid lipid and vigorous stirring is maintained, the mixture is then stirred with more speed and for several minutes . If the powdered ingredients have a particle size that is larger than 200 µm, the mixture would start to separate. So, the particle size of the powdered ingredients need to be maintained at less than 200 µm, for the mixture to not readily separate .
The most common RUTFs are made of four ingredients: sugar, dried skimmed milk, oil and vitamin and mineral supplement (CMV) . Other qualities that RUTFs should have include that their texture is soft or crushable and taste is acceptable and suitable for children of young ages. RUTFs should also be ready to eat without the need for them to be cooked. A very important characteristic is that the RUTFs have a long shelf-life and that they are micro-organism contamination resistant, without the need for expensive packaging. Since the ingredients need to be suspended in liquid, the liquid used in producing RUTFs needs to be fat/lipid. 50% of the protein forming RUTFs should come from dairy products . An example of a nutritional composition of a Ready-to-Use Therapeutic Foods is as follows:
Nutritional composition
Moisture content 2.5% maximum
Energy 520-550 Kcal/100g
Proteins 10 to 12 % total energy
Lipids 45 to 60 % total energy
Sodium 290 mg/100g maximum
Potassium 1100 to 1400 mg/100g
Calcium 300 to 600 mg/100g
Phosphorus (excluding phytate) 300 to 600 mg/100g
Magnesium 80 to 140 mg/100g
Iron 10 to 14 mg/100g
Zinc 11 to 14 mg/100g
Copper 1.4 to 1.8 mg/100g
Selenium 20 to 40 µg
Iodine 70 to 140 µg/100g
Vitamin A 0.8 to 1.1 mg/100g
Vitamin D 15 to 20 µg/100g
Vitamin E 20 mg/100g minimum
Vitamin K 15 to 30 µg/100g
Vitamin B1 0.5 mg/100g minimum
Vitamin B2 1.6 mg/100g minimum
Vitamin C 50 mg/100g minimum
Vitamin B6 0.6 mg/100g minimum
Vitamin B12 1.6 µg/100g minimum
Folic acid 200 µg/100g minimum
Niacin 5 mg/100g minimum
Pantothenic acid 3 mg/100g minimum
Biotin 60 µg/100g minimum
n-6 fatty acids 3% to 10% of total energy
n-3 fatty acids 0.3 to 2.5% of total energy

Examples

  • Plumpy'nut
    Plumpy'nut
    Plumpy'nut is a peanut-based paste in a plastic wrapper for treatment of severe acute malnutrition manufactured by a French company, Nutriset...

    , the first solid RUTF to be developed , made in France since 1996 for treatment of severe acute malnutrition.
  • Medika mamba, an enriched peanut butter therapeutic food.
  • Ensure
    Ensure
    Ensure is the brand name of a family of liquid nutritional supplements manufactured by Abbott Laboratories.The beverages are meant to be administered orally, or through nasogastric tubes, directly to the recipient's stomach....

    , a fortified milkshake drink designed primarily for the elderly.
  • Fortisip
    Fortisip
    Fortisip is a therapeutic food manufactured by Nutricia. It is a ready-made milkshake style drink meant for consumption by people who cannot consume enough solid food to maintain a balanced diet; when appetite is poor and nutritional requirements are not being met through ordinary food, many people...

    , a milkshake-style drink similar to Ensure.
  • Energyzip, also a milkshake-style drink like Ensure designed for elderly and AIDS/cancer patients.
  • TwoCal
  • BP-100, a nutrient-fortified wheat-and oat bar designed to provide a similar nutritional profile to the WHO's F-100
    F-100 (food)
    F-100 and F-75 are therapeutic milk products designed to treat severe malnutrition. In 1994 Action Against Hunger / Action Contre la Faim pioneered the use of milk formula F-100 for the treatment of severe acute malnutrition...

    .
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