Thiethylperazine
Encyclopedia
Thiethylperazine is an antiemetic
of the phenothiazine
class. Though it was never licensed or used as an antipsychotic
, it may have such effects.
Thiethylperazine activates the transport protein ABCC1
that clears beta-amyloid from brains of mice.
Antiemetic
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer....
of the phenothiazine
Phenothiazine
Phenothiazine is an organic compound that occurs in various antipsychotic and antihistaminic drugs. It has the formula S2NH. This yellow tricyclic compound is soluble in acetic acid, benzene, and ether. The compound is related to the thiazine-class of heterocyclic compounds...
class. Though it was never licensed or used as an antipsychotic
Antipsychotic
An antipsychotic is a tranquilizing psychiatric medication primarily used to manage psychosis , particularly in schizophrenia and bipolar disorder. A first generation of antipsychotics, known as typical antipsychotics, was discovered in the 1950s...
, it may have such effects.
Thiethylperazine activates the transport protein ABCC1
ABCC1
Multidrug resistance-associated protein 1 is a protein that in humans is encoded by the ABCC1 gene.ABCC1 clears beta-amyloid from brains of mice and can be activated by thiethylperazine.- External links :...
that clears beta-amyloid from brains of mice.