Tiazofurin
Encyclopedia
Tiazofurin is an inhibitor
of IMP dehydrogenase
. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.
Enzyme inhibitor
An enzyme inhibitor is a molecule that binds to enzymes and decreases their activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and pesticides...
of IMP dehydrogenase
IMP dehydrogenase
IMP dehydrogenase is an enzyme that converts inosine monophosphate to xanthosine monophosphate:The structure of this enzyme is composed of a TIM barrel domain with two CBS domains inserted within a loop.It is inhibited by Mycophenolic acid.- Examples :...
. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.