Tight junction protein 1
Encyclopedia
Tight junction protein ZO-1 is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the TJP1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

Tight junction protein 1 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with F11 receptor
F11 receptor
Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. KDR has also been designated as CD321 .-Interactions:...

, Gap junction protein, alpha 1
Gap junction protein, alpha 1
-Interactions:Gap junction protein, alpha 1 has been shown to interact with MAPK7, Caveolin 1, Tight junction protein 1 CSNK1D, and PTPmu .-Further reading:...

, MLLT4
MLLT4
Afadin is a protein that in humans is encoded by the MLLT4 gene.-Interactions:MLLT4 has been shown to interact with F11 receptor, RAP1A, LMO2, EPHB3, RAP1GAP, PVRL1, PVRL3, USP9X, SORBS1, BCR gene, Tight junction protein 1, Profilin 1, HRAS and SSX2IP.-Further reading:...

, Occludin
Occludin
Occludin is a protein that in humans is encoded by the OCLN gene.Occludin is a 65-kDa integral plasma-membrane protein located at the tight junctions, described for the first time in 1993 by Shoichiro Tsukita...

, TJP3
TJP3
Tight junction protein ZO-3 is a protein that in humans is encoded by the TJP3 gene.-Interactions:TJP3 has been shown to interact with Tight junction protein 1.-Further reading:...

, GJA3
GJA3
Gap junction alpha-3 protein is a protein that in humans is encoded by the GJA3 gene.-Interactions:GJA3 has been shown to interact with Tight junction protein 1....

, KIRREL
KIRREL
Kin of IRRE-like protein 1 is a protein that in humans is encoded by the KIRREL gene.-Interactions:KIRREL has been shown to interact with Nephrin and Tight junction protein 1.-Further reading:...

, Tight junction protein 2
Tight junction protein 2
Tight junction protein ZO-2 is a protein that in humans is encoded by the TJP2 gene.-Interactions:Tight junction protein 2 has been shown to interact with Tight junction protein 1, Band 4.1 and Occludin.-Further reading:...

 and GJA8
GJA8
Gap junction alpha-8 protein is a protein that in humans is encoded by the GJA8 gene. It is also known as connexin 50.-Interactions:GJA8 has been shown to interact with Tight junction protein 1....

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Further reading

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