Torezolid is an oxazolidinone drug in phase-II clinical trial

Clinical trial

Clinical trials are a set of procedures in medical research and drug development that are conducted to allow safety and efficacy data to be collected for health interventions...

s for complicated skin and skin-structure infections

Complicated skin and skin-structure infections

Complicated skin and skin structure infections also known as cSSSIs are the name for common infections treated in the hospital setting. The main treatment of these infections is antimicrobial therapy along with possible surgery...

 (cSSSI), including those caused by Methicillin-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus is a bacterium responsible for several difficult-to-treat infections in humans. It is also called multidrug-resistant Staphylococcus aureus and oxacillin-resistant Staphylococcus aureus...

 (MRSA).

The prodrug is called "TR-701", while the active ingredient is called "TR-700".

a phase III trial (under SPA

FDA Special Protocol Assessment

A Special Protocol Assessment is a declaration from the Food and Drug Administration that an uncompleted Phase III trial's design, clinical endpoints, and statistical analyses are acceptable for FDA approval....

) was mid way through patient recruitment. The trial tests 200mg once-daily Torezolid against 600mg twice-daily Zyvox (linezolid

Linezolid

Linezolid is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics...

).

the first phase III trial should report in early 2012, and a second phase III trial has started recruiting.