Transcription Factor II E
Encyclopedia
Transcription factor II E (TFIIE) is one of several general transcription factor
s that make up the RNA polymerase II
preinitiation complex
.
Transcription Factor II E is encoded by the GTF2E1
and GTF2E2
genes. TFIIE is thought to be involved in DNA melting at the promoter: it contains a zinc ribbon motif that can bind single stranded DNA.
General transcription factor
General transcription factors or basal transcription factors are protein transcription factors that have been shown to be important in the transcription of class II genes to mRNA templates...
s that make up the RNA polymerase II
RNA polymerase II
RNA polymerase II is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. A 550 kDa complex of 12 subunits, RNAP II is the most studied type of RNA polymerase...
preinitiation complex
Preinitiation complex
The preinitiation complex is a large complex of proteins that is necessary for the transcription of protein-coding genes in eukaryotes...
.
Transcription Factor II E is encoded by the GTF2E1
GTF2E1
General transcription factor IIE subunit 1 , also known as transcription initiation factor IIE subunit alpha , is a protein that in humans is encoded by the GTF2E1 gene.-Further reading:...
and GTF2E2
GTF2E2
General transcription factor IIE subunit 2 , also known as transcription initiation factor IIE subunit beta , is a protein that in humans is encoded by the GTF2E2 gene.-Further reading:...
genes. TFIIE is thought to be involved in DNA melting at the promoter: it contains a zinc ribbon motif that can bind single stranded DNA.