Triamcinolone
Encyclopedia
Triamcinolone is a long-acting synthetic
corticosteroid
given orally, by injection
, inhalation, or as a topical
ointment or cream.
, psoriasis
, arthritis
, allergies, ulcerative colitis
, lupus
, sympathetic ophthalmia
, temporal arteritis
, uveitis
, and ocular
inflammation
, visualization during vitrectomy
and the prevention of asthma
attacks. It will not treat an asthma attack once it has already begun.
Prior to 2007 it was manufactured under the name Azmacort as a corticosteroid
inhaler
for asthma
long-term care. The patent holder, Sanofi, sold it under the brand name Nasacort.
In 2010, TEVA and Perrigo launched the first generic inhalable triamcinolone.
Triamcinolone is used to alleviate infection-induced eczema in fungal skin infections in the combination drug of econazole/triamcinolone
.
Triamcinolone acetonide
is one of the ingredients of Ledermix - an endodontic (tooth's root canal) lotion used between sessions.
, benetonide, furetonide, hexacetonide and diacetate
.
Triamcinolone acetonide is a more potent type of triamcinolone, being about eight times as effective as prednisone
.
Chemical synthesis
In chemistry, chemical synthesis is purposeful execution of chemical reactions to get a product, or several products. This happens by physical and chemical manipulations usually involving one or more reactions...
corticosteroid
Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte...
given orally, by injection
Injection (medicine)
An injection is an infusion method of putting fluid into the body, usually with a hollow needle and a syringe which is pierced through the skin to a sufficient depth for the material to be forced into the body...
, inhalation, or as a topical
Topical
In medicine, a topical medication is applied to body surfaces such as the skin or mucous membranes such as the vagina, anus, throat, eyes and ears.Many topical medications are epicutaneous, meaning that they are applied directly to the skin...
ointment or cream.
Uses
Triamcinolone is used to treat several different medical conditions, such as eczemaEczema
Eczema is a form of dermatitis, or inflammation of the epidermis . In England, an estimated 5.7 million or about one in every nine people have been diagnosed with the disease by a clinician at some point in their lives.The term eczema is broadly applied to a range of persistent skin conditions...
, psoriasis
Psoriasis
Psoriasis is an autoimmune disease that appears on the skin. It occurs when the immune system mistakes the skin cells as a pathogen, and sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis is not contagious. However, psoriasis has been linked to an increased risk of...
, arthritis
Arthritis
Arthritis is a form of joint disorder that involves inflammation of one or more joints....
, allergies, ulcerative colitis
Ulcerative colitis
Ulcerative colitis is a form of inflammatory bowel disease . Ulcerative colitis is a form of colitis, a disease of the colon , that includes characteristic ulcers, or open sores. The main symptom of active disease is usually constant diarrhea mixed with blood, of gradual onset...
, lupus
Lupus
Lupus most commonly refers to the disease systemic lupus erythematosus.Lupus may also refer to:-Medicine:* Lupus erythematosus, a chronic autoimmune disease with several different forms...
, sympathetic ophthalmia
Sympathetic ophthalmia
Sympathetic ophthalmia is a granulomatous uveitis of both eyes following trauma to one eye. It can leave the patient completely blind. Symptoms may develop from days to several years after a penetrating eye injury. See also the reviews by Damico et al. , Chu and Foster , and Friedlaender et al...
, temporal arteritis
Temporal arteritis
Giant-cell arteritis or Horton disease is an inflammatory disease of blood vessels most commonly involving large and medium arteries of the head...
, uveitis
Uveitis
Uveitis specifically refers to inflammation of the middle layer of the eye, termed the "uvea" but in common usage may refer to any inflammatory process involving the interior of the eye....
, and ocular
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...
inflammation
Inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...
, visualization during vitrectomy
Vitrectomy
Vitrectomy is a surgery to remove some or all of the vitreous humor from the eye. Anterior vitrectomy entails removing small portions of the vitreous from the front structures of the eye—often because these are tangled in an intraocular lens or other structures...
and the prevention of asthma
Asthma
Asthma is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms include wheezing, coughing, chest tightness, and shortness of breath...
attacks. It will not treat an asthma attack once it has already begun.
Prior to 2007 it was manufactured under the name Azmacort as a corticosteroid
Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte...
inhaler
Inhaler
An inhaler or puffer is a medical device used for delivering medication into the body via the lungs. It is mainly used in the treatment of asthma and Chronic Obstructive Pulmonary Disease . Zanamivir , used to treat influenza, must be administered via inhaler...
for asthma
Asthma
Asthma is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms include wheezing, coughing, chest tightness, and shortness of breath...
long-term care. The patent holder, Sanofi, sold it under the brand name Nasacort.
In 2010, TEVA and Perrigo launched the first generic inhalable triamcinolone.
Triamcinolone is used to alleviate infection-induced eczema in fungal skin infections in the combination drug of econazole/triamcinolone
Econazole/triamcinolone
Econazole/triamcinolone is a combination drug, consisting of econazole and triamcinolone Econazole/triamcinolone is a combination drug, consisting of econazole (an imidazole antifungal) and triamcinolone Econazole/triamcinolone is a combination drug, consisting of econazole (an imidazole...
.
Triamcinolone acetonide
Triamcinolone acetonide
Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions and to relieve the discomfort of mouth sores. It is a more potent type of triamcinolone, being about 8 times as effective as prednisone.-Medical use:...
is one of the ingredients of Ledermix - an endodontic (tooth's root canal) lotion used between sessions.
Forms
Different triamcinolone salts are available, including acetonideAcetone
Acetone is the organic compound with the formula 2CO, a colorless, mobile, flammable liquid, the simplest example of the ketones.Acetone is miscible with water and serves as an important solvent in its own right, typically as the solvent of choice for cleaning purposes in the laboratory...
, benetonide, furetonide, hexacetonide and diacetate
Acetate
An acetate is a derivative of acetic acid. This term includes salts and esters, as well as the anion found in solution. Most of the approximately 5 billion kilograms of acetic acid produced annually in industry are used in the production of acetates, which usually take the form of polymers. In...
.
Triamcinolone acetonide is a more potent type of triamcinolone, being about eight times as effective as prednisone
Prednisone
Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug. It is used to treat certain inflammatory diseases and some types of cancer, but has significant adverse effects...
.