Troponin T
Encyclopedia
Troponin T is a part of the troponin
complex. It binds to tropomyosin
, interlocking them to form a troponin-tropomyosin complex.
The tissue specific subtypes are:
Troponin T binds to tropomyosin and helps position it on actin . And in a less complicated light, Troponin T modulates contraction of striated muscle
Troponin T was discovered by the German
physician Hugo A. Katus at the University of Heidelberg. He developed the troponin T assay.
Troponin
400px|thumb|right|alt = Colored dice with checkered background|Ribbon representation of the human cardiac troponin core complex in the calcium-saturated form...
complex. It binds to tropomyosin
Tropomyosin
Tropomyosin is an actin-binding protein that regulates actin mechanics. It is important, among other things, for muscle contraction. Tropomyosin, along with the troponin complex, associate with actin in muscle fibers and regulate muscle contraction by regulating the binding of myosin...
, interlocking them to form a troponin-tropomyosin complex.
The tissue specific subtypes are:
- Slow skeletal troponin T1, TNNT1TNNT1Troponin T, slow skeletal muscle is a protein that in humans is encoded by the TNNT1 gene.-External links:* -Further reading:...
(19q13.4) - Cardiac troponin T2, TNNT2TNNT2Troponin T type 2 , also known as TNNT2, is a protein which in humans is encoded by the TNNT2 gene.The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to...
(1q32) - Fast skeletal troponin T3, TNNT3TNNT3Troponin T, fast skeletal muscle is a protein that in humans is encoded by the TNNT3 gene.-Further reading:...
(11p15.5)
Troponin T binds to tropomyosin and helps position it on actin . And in a less complicated light, Troponin T modulates contraction of striated muscle
Troponin T was discovered by the German
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...
physician Hugo A. Katus at the University of Heidelberg. He developed the troponin T assay.