• Dimensional lumber, specifically a timber measuring 2 by 2 inches of any given length
• Two-wheel drive
  Two-wheel drive
  Two wheel drive or 2WD describes vehicles with a drivetrain that allows two wheels to receive power from the engine simultaneously.-Four wheeled vehicles:...
  
  , a designation of motor vehicle
• Two by Twos, a non-denominational house church also known as The Truth, The Way and Cooneyites
• 2by2 (lottery)
  2by2 (lottery)
  2by2 is a lottery game played in Kansas, Nebraska, and North Dakota. It is drawn nightly at the Iowa headquarters of the Multi-State Lottery Association Kansas and Nebraska started the game in 2002; North Dakota joined in 2006....
  
  , a lottery game offered in US

In the arts

• Two by Two (musical)
  Two by Two (musical)
  Two By Two is a Broadway musical with a book by Peter Stone, lyrics by Martin Charnin, and music by Richard Rodgers.Based on Clifford Odets's play The Flowering Peach, it tells the story of Noah's preparations for the Great Flood and its aftermath....
  
  , a Broadway show with music by Richard Rodgers
• Two by Two
  Two By Two (album)
  Two by Two was Blue Zoo's 1983 album and featured their October 1982 UK hit "Cry Boy Cry".The album was produced by Talk Talk's Tim Friese-Greene.-Track listing:# "Cry Boy Cry"# "John's Lost"# "Far Cry"...
  
  , a 1983 album by Blue Zoo
  Blue Zoo
  Blue Zoo were a British new wave band, operating between 1980 and 1985.-Career:Formed in 1980, their original band name was Modern Jazz, and they released a single "In My Sleep " in that year....
  
  
• Two by Two, (Rugrats episode)
• Two By Two, a song by Quasi
  Quasi
  Quasi is an American indie rock band formed in Portland, Oregon in 1993 by ex-husband and wife Sam Coomes and Janet Weiss . Since 2007 the group has been a trio, following the addition of bassist Joanna Bolme.-History:In 1990 , Coomes, Weiss, and Brad Pedinov formed the band Motorgoat...
  
  
• 2x2 (TV channel)
  2x2 (TV channel)
  2×2 is Russia's oldest private entertainment TV channel. Since 2007 it specializes in animated series.-History:Founded in 1989 and first aired on September 27, 1990, 2×2 became the first commercial television in the Soviet Union....
  
  , a TV channel in Russia
  Russia
  Russia or , officially known as both Russia and the Russian Federation , is a country in northern Eurasia. It is a federal semi-presidential republic, comprising 83 federal subjects...
  
  
• "Two by Two", from the musical The Book of Mormon