The Big League is the second tier in Ugandan association football. The league will be contested by 16 teams.

The maiden tournament is scheduled to take place in March 2010.

Elgon Group

Gulu United FC (Gulu)
UTODA FC (Kampala)
Bishop Nankyama FC (Bukalasa)
Samba Boys FC (Yumbe)
Jinja MC Hippos (Jinja)
Mbale Heroes FC (Mbale)
Sharing Youth FC (Kampala)
Devine Waters FC (Apac)

Rwenzori Group

Maroons FC (Kampala)
Misindye FC (Mukono)
KASE FC (Kampala)
Ndejje University FC (Luwero)
Jinja Arsenal FC (Jinja)
Mbarara United FC (Mbarara)
Masaka Municipal Council (Masaka)
Fort Hills FC (Fort Portal)