Ulinastatin
Encyclopedia
Ulinastatin is a glycoprotein which acts as a trypsin inhibitor
. It can be derived from urine
or it can be synthetically produced. It may be effective in treatment of acute pancreatitis
, chronic pancreatitis
, toxic shock, Stevens–Johnson syndrome and toxic epidermal necrolysis
(TEN). Currently, the drug is being used for research purposes only.
Trypsin inhibitor
Trypsin inhibitors are chemicals that reduce the availability of trypsin, an enzyme essential to nutrition of many animals, including humans.There are four commercial sources of trypsin inhibitors....
. It can be derived from urine
Urine
Urine is a typically sterile liquid by-product of the body that is secreted by the kidneys through a process called urination and excreted through the urethra. Cellular metabolism generates numerous by-products, many rich in nitrogen, that require elimination from the bloodstream...
or it can be synthetically produced. It may be effective in treatment of acute pancreatitis
Acute pancreatitis
Acute pancreatitis or acute pancreatic necrosis is a sudden inflammation of the pancreas. It can have severe complications and high mortality despite treatment...
, chronic pancreatitis
Chronic pancreatitis
Chronic pancreatitis is a long-standing inflammation of the pancreas that alters its normal structure and functions. It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption....
, toxic shock, Stevens–Johnson syndrome and toxic epidermal necrolysis
Toxic epidermal necrolysis
Toxic epidermal necrolysis is a rare, life-threatening dermatological condition that is usually induced by a reaction to medications...
(TEN). Currently, the drug is being used for research purposes only.