United States Army Medical Unit
Encyclopedia
The United States Army Medical Unit (1956-1969) — a now defunct medical research unit for biodefense
Biodefense
Biodefense refers to short term, local, usually military measures to restore biosecurity to a given group of persons in a given area who are, or may be, subject to biological warfare— in the civilian terminology, it is a very robust biohazard response. It is technically possible to apply...

 — was at Fort Detrick
Fort Detrick
Fort Detrick is a U.S. Army Medical Command installation located in Frederick, Maryland, USA. Historically, Fort Detrick was the center for the United States' biological weapons program ....

, Maryland
Maryland
Maryland is a U.S. state located in the Mid Atlantic region of the United States, bordering Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware to its east...

, USA. In contrast to the U.S. Army Biological Warfare Laboratories
United States Army Biological Warfare Laboratories
The U.S. Army Biological Warfare Laboratories were a suite of research laboratories and pilot plant centers operating at Camp Detrick, Maryland, USA beginning in 1943 under the control of the U.S. Army Chemical Corps Research and Development Command...

 (1943–1969), also at Fort Detrick, the USAMU's mission was purely to develop defensive measures against bio-agents, as opposed to weapons development. The USAMU was the predecessor to today's USAMRIID.

History

The U.S. Army Medical Unit (USAMU or AMU) was originally established on 20 June 1956 as a separate Class II activity under the jurisdiction of Walter Reed Army Medical Center
Walter Reed Army Medical Center
The Walter Reed Army Medical Center was the United States Army's flagship medical center until 2011. Located on 113 acres in Washington, D.C., it served more than 150,000 active and retired personnel from all branches of the military...

 (WRAMC). The first USAMU commander was Col. William D. Tigertt. One of the USAMU’s first responsibilities was to oversee all aspects of Project CD-22, the exposure of volunteers to aerosols containing a highly pathogenic strain of Coxiella burnetii
Coxiella burnetii
Coxiella burnetii is an obligate intracellular bacterial pathogen, and is the causative agent of Q fever. The genus Coxiella is morphologically similar to Rickettsia, but with a variety of genetic and physiological differences. C...

, the causal agent of Q fever
Q fever
Q fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects humans and other animals. This organism is uncommon but may be found in cattle, sheep, goats and other domestic mammals, including cats and dogs...

. One pre-existing research project, Operation Whitecoat
Operation Whitecoat
Operation Whitecoat was the name given to a medical research program carried out by the US Army at Fort Detrick, Maryland during the period 1954–1973. The program involved conducting medical research using volunteer enlisted personnel who eventually became nicknamed "White Coats"...

 (1954-1973), outlasted the USAMU. (It was a medical research program using volunteer enlisted personnel — all conscientious objector
Conscientious objector
A conscientious objector is an "individual who has claimed the right to refuse to perform military service" on the grounds of freedom of thought, conscience, and/or religion....

s.) General Order 9, dated 29 September 1958, Office of The Surgeon General, assigned the USAMU to Headquarters, U.S. Army Medical Research and Development Command (USAMRDC). In 1961, Col. Dan Crozier assumed command of the USAMU. Modern principles of biosafety
Biosafety
Biosafety: prevention of large-scale loss of biological integrity, focusing both on ecology and human health .Biosafety is related to several fields:*In ecology ,...

 and biocontainment
Biocontainment
The concept of biocontainment, also called laboratory biosafety, pertains to microbiology laboratories in which the physical containment of highly pathogenic organisms or agents is required, usually by isolation in environmentally and biologically secure cabinets or rooms, to prevent accidental...

 were pioneered at Fort Detrick throughout the 1960s by a number of scientists led by Arnold G. Wedum. General Order No. 6, dated 27 January 1969, Office of The Surgeon General, redesignated the USAMU as the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) still assigned to USAMRDC.
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