VE (nerve agent)
Encyclopedia
VE is a "V-series" nerve agent
Nerve agent
Nerve agents are a class of phosphorus-containing organic chemicals that disrupt the mechanism by which nerves transfer messages to organs...

 closely related to the better-known VX nerve agent
VX (nerve agent)
VX, IUPAC name O-ethyl S-[2-ethyl] methylphosphonothioate, is an extremely toxic substance whose only application is in chemical warfare as a nerve agent. As a chemical weapon, it is classified as a weapon of mass destruction by the United Nations in UN Resolution 687...

.

Like most of the agents in the V-series (with the exception of VX), VE has not been extensively studied outside of military science
Military science
Military science is the process of translating national defence policy to produce military capability by employing military scientists, including theorists, researchers, experimental scientists, applied scientists, designers, engineers, test technicians, and military personnel responsible for...

. Little is known about this compound other than its chemical formula.

It is commonly theorized that the so called "second-generation" V series agents came from a cold war
Cold War
The Cold War was the continuing state from roughly 1946 to 1991 of political conflict, military tension, proxy wars, and economic competition between the Communist World—primarily the Soviet Union and its satellite states and allies—and the powers of the Western world, primarily the United States...

 era Russia
Russia
Russia or , officially known as both Russia and the Russian Federation , is a country in northern Eurasia. It is a federal semi-presidential republic, comprising 83 federal subjects...

n chemical weapons development program. They may have been developed sometime between 1950 and 1990. They have similar lethal dose levels to VX (between 10-50 mg) and have similar symptoms and method of action to other nerve agents that act on cholinesterase
Cholinesterase
In biochemistry, cholinesterase is a family of enzymes that catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation.-Types:...

, and treatment remains the same, but the window for effectively treating second generation V series seizure
Seizure
An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain". The outward effect can be as dramatic as a wild thrashing movement or as mild as a brief loss of awareness...

s is shorter. In addition to the standard seizures, some of the second generation V series agents are known to cause coma
Coma
In medicine, a coma is a state of unconsciousness, lasting more than 6 hours in which a person cannot be awakened, fails to respond normally to painful stimuli, light or sound, lacks a normal sleep-wake cycle and does not initiate voluntary actions. A person in a state of coma is described as...

s.
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