William T. Wickner
Encyclopedia
William T. Wickner born March 13, 1946, the James C. Chilcott '20 Distinguished Professor of Biochemistry at Dartmouth Medical School
Dartmouth Medical School
Dartmouth Medical School is the medical school of Dartmouth College, located in Hanover, New Hampshire, in the United States. The fourth-oldest medical school in the United States, Dartmouth Medical School was founded in 1797 by New England physician Nathan Smith and grew steadily over the course...

, is an authority on membrane fusion and inheritance, which is a fundamental problem in eukaryotic and bacterial cell biology.

Bill Wickner, brother of prion biologist Reed Wickner
Reed Wickner
Reed B. Wickner is an American yeast geneticist. In 1994 he proposed that the [PSI+] and [URE3] phenotypes in Saccharomyces cerevisiae, a form of budding yeast, were caused by prion forms of native proteins. Specifically, the sup35p protein....

 and Cornell graduate Nancy Wickner Kogan, is a 1967 graduate of Yale University
Yale University
Yale University is a private, Ivy League university located in New Haven, Connecticut, United States. Founded in 1701 in the Colony of Connecticut, the university is the third-oldest institution of higher education in the United States...

 (chemistry) and a 1973 M.D. graduate of Harvard Medical School
Harvard Medical School
Harvard Medical School is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts....

. At Harvard, he worked with Eugene Kennedy.

He conducted post-doctoral research with Arthur Kornberg
Arthur Kornberg
Arthur Kornberg was an American biochemist who won the Nobel Prize in Physiology or Medicine 1959 for his discovery of "the mechanisms in the biological synthesis of deoxyribonucleic acid " together with Dr. Severo Ochoa of New York University...

 at Stanford University
Stanford University
The Leland Stanford Junior University, commonly referred to as Stanford University or Stanford, is a private research university on an campus located near Palo Alto, California. It is situated in the northwestern Santa Clara Valley on the San Francisco Peninsula, approximately northwest of San...

, discovering the role of an RNA primer in the replication of DNA. He began his independent research career as a Mellon senior fellow at Stanford in 1974, where he initiated studies of asymmetric membrane assembly in bacteria and viral assembly.

Wickner then spent 17 years on the faculty of UCLA, during which time he earned honors including an American Cancer Society
American Cancer Society
The American Cancer Society is the "nationwide community-based voluntary health organization" dedicated, in their own words, "to eliminating cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer, through research, education, advocacy, and...

 Faculty Research Award, a Guggenheim Fellowship and an NIH Merit Award.

In 1993, he moved to Dartmouth Medical School
Dartmouth Medical School
Dartmouth Medical School is the medical school of Dartmouth College, located in Hanover, New Hampshire, in the United States. The fourth-oldest medical school in the United States, Dartmouth Medical School was founded in 1797 by New England physician Nathan Smith and grew steadily over the course...

, where he became chair of the Biochemistry Department and was elected to the National Academy of Sciences
United States National Academy of Sciences
The National Academy of Sciences is a corporation in the United States whose members serve pro bono as "advisers to the nation on science, engineering, and medicine." As a national academy, new members of the organization are elected annually by current members, based on their distinguished and...

 in 1996. Dr. Wickner is also a foreign associate of the European Molecular Biology Organization and a member of the American Academy of Arts and Sciences.

Wickner has trained many successful scientists including Barbara Conradt, Elliott Crooke, Franz-Ulrich Hartl
Franz-Ulrich Hartl
Franz-Ulrich Hartl is a German biochemist and Managing Director of the Max Planck Institute of Biochemistry. He is known for his pioneering work in the field of protein-mediated protein folding....

, Daniel Klionsky, Roland Lill, Gail Mandel, Janet Shaw
Janet Shaw
Janet Shaw is a Paralympic cycling competitor from Australia. She won a bronze medal at the 2004 Athens Games in theWomen's Road Race / Time Trial Tandem B1-3 event.-References:...

, Pamela Silver
Pamela Silver
Pamela Silver is a Professor in the Department of Systems Biology at Harvard Medical School. She is the first Director of the Harvard University PhD Program in Systems Biology. Silver is also a core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University...

, Gunnar von Heijne
Gunnar von Heijne
Nils Gunnar Hansson von Heijne, born June 10, 1951 in Gothenburg, is a Swedish chemist.Gunnar von Heijne graduated 1975 with a Master of Science degree in chemistry and chemical engineering from the Royal Institute of Technology...

 and Lois Weisman.

Wickner's Lab currently explores yeast vacuole fusion as a model for membrane fusion.

External links

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