XPA
Encyclopedia
DNA repair protein complementing XP-A cells is a protein
that in humans is encoded by the XPA gene
.
with ERCC1
, Replication protein A1 and XAB2
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the XPA gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
XPA has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with ERCC1
ERCC1
DNA excision repair protein ERCC-1 is a protein that in humans is encoded by the ERCC1 gene.- Function :The function of the ERCC1 protein is predominantly in nucleotide excision repair of damaged DNA...
, Replication protein A1 and XAB2
XAB2
Pre-mRNA-splicing factor SYF1 is a protein that in humans is encoded by the XAB2 gene.-Interactions:XAB2 has been shown to interact with ERCC8 and XPA.-Further reading:...
.