Yasunori Hayashi
Encyclopedia
is a Japanese neuroscientist
who was born in Aichi and grew up in Tokyo
. He is leading his research group in RIKEN
Brain Science Institute, Japan.
Neuroscientist
A neuroscientist is an individual who studies the scientific field of neuroscience or any of its related sub-fields...
who was born in Aichi and grew up in Tokyo
Tokyo
, ; officially , is one of the 47 prefectures of Japan. Tokyo is the capital of Japan, the center of the Greater Tokyo Area, and the largest metropolitan area of Japan. It is the seat of the Japanese government and the Imperial Palace, and the home of the Japanese Imperial Family...
. He is leading his research group in RIKEN
RIKEN
is a large natural sciences research institute in Japan. Founded in 1917, it now has approximately 3000 scientists on seven campuses across Japan, the main one in Wako, just outside Tokyo...
Brain Science Institute, Japan.
Education and research history
- 1984–1990 MD, Kyoto UniversityKyoto University, or is a national university located in Kyoto, Japan. It is the second oldest Japanese university, and formerly one of Japan's Imperial Universities.- History :...
Faculty of Medicine - 1990–1994 PhD, Institute for Immunology and Department of Pharmacology, Kyoto University Faculty of Medicine
- 1994–1996 Postdoctral Fellow, Department of Neurophysiology, Institute for Brain Research, Faculty of Medicine, University of TokyoUniversity of Tokyo, abbreviated as , is a major research university located in Tokyo, Japan. The University has 10 faculties with a total of around 30,000 students, 2,100 of whom are foreign. Its five campuses are in Hongō, Komaba, Kashiwa, Shirokane and Nakano. It is considered to be the most prestigious university...
- 1996–2000 Postdoctral Fellow, Cold Spring Harbor LaboratoryCold Spring Harbor LaboratoryThe Cold Spring Harbor Laboratory is a private, non-profit institution with research programs focusing on cancer, neurobiology, plant genetics, genomics and bioinformatics. The Laboratory has a broad educational mission, including the recently established Watson School of Biological Sciences. It...
- 2000–2009 Assistant Professor (joint), RIKENRIKENis a large natural sciences research institute in Japan. Founded in 1917, it now has approximately 3000 scientists on seven campuses across Japan, the main one in Wako, just outside Tokyo...
-MIT Neuroscience Research Center, The Picower Institute for Learning and MemoryPicower Institute for Learning and MemoryThe Picower Institute for Learning and Memory is, along with the McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, one of the three neuroscience groups at MIT...
, Department of Brain and Cognitive Sciences, Massachusetts Institute of TechnologyMassachusetts Institute of TechnologyThe Massachusetts Institute of Technology is a private research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing a total of 32 academic departments, with a strong emphasis on scientific and technological education and research.Founded in 1861 in... - 2000–2004 Senior Scientist (joint), Brain Science Institute, RIKEN
- 2004–2009 Unit Leader (joint), Brain Science Institute, RIKEN
- 2009 – current Team Leader, Brain Science Institute, RIKEN
Past accomplishments
- Regulation of adrenal tyrosine hydroxylaseTyrosine hydroxylaseTyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to dihydroxyphenylalanine . It does so using tetrahydrobiopterin as a coenzyme. DOPA is a precursor for dopamine, which, in turn, is a precursor for norepinephrine ...
under hypoxic condition - Cloning and functional analysis of prostanoidProstanoidProstanoid is the term used to describe a subclass of eicosanoids consisting of: the prostaglandins , the thromboxanes and the prostacyclins - Biosynthesis : Cyclooxygenase catalyzes the conversion of the free essential fatty acids to...
receptorReceptor (biochemistry)In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism... - Pharmacological analyses of metabotropic glutamate receptorMetabotropic glutamate receptorThe metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs...
- Activity dependent trafficking of AMPA type glutamate receptorGlutamate receptorGlutamate receptors are synaptic receptors located primarily on the membranes of neuronal cells. Glutamate is one of the 20 amino acids used to assemble proteins and as a result is abundant in many areas of the body, but it also functions as a neurotransmitter and is particularly abundant in the...
as a mechanism of hippocampalHippocampusThe hippocampus is a major component of the brains of humans and other vertebrates. It belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory and spatial navigation. Humans and other mammals have two hippocampi, one in...
LTPLTP- Science and technology :* Lunar Transient Phenomena, a short-lived change in appearance of Earth's moon* Long-tailed pair, a differential pair amplifier* Lightweight Telephony Protocol, a signaling protocol... - Structural plasticity of dendritic spine and its molecular mechanisms
- Molecular cloning and analysis of motoneuron specific NMDA receptorNMDA receptorThe NMDA receptor , a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function....
subtype NR3BGRIN3BGlutamate [NMDA] receptor subunit 3B is a protein that in humans is encoded by the GRIN3B gene.... - Retrograde regulation of synaptic release probability by cell adhesion molecules
- Structural elucidation of high-order structure of postsynaptic densityPostsynaptic densityThe postsynaptic density is a protein dense specialization attached to the postsynaptic membrane. PSDs were originally identified by electron microscopy as an electron-dense region at the membrane of a postsynaptic neuron...
Awards and honors
- 1998 Young Investigator Award from Japanese Pharmacological Society
- 2008 JSPS Prize for Young Investigators
- 2008 Japan Academy Medal