Zibotentan
Encyclopedia
Zibotentan is an anti-cancer candidate. It is a endothelin receptor antagonist
.
It failed a phase III clinical trial for prostate cancer
but other trials are planned. Tolerability of zibotentan plus docetaxel has been evaluated.
Endothelin receptor antagonist
A endothelin receptor antagonist is a drug that blocks endothelin receptors.Three main kinds of ERAs exist:* selective ETA receptor antagonists , which affect endothelin A receptors....
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It failed a phase III clinical trial for prostate cancer
Prostate cancer
Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostate cancers. The cancer cells may metastasize from the prostate to other parts of the body, particularly...
but other trials are planned. Tolerability of zibotentan plus docetaxel has been evaluated.