105 Mile House is an unincorporated settlement in the South Cariboo

Cariboo

The Cariboo is an intermontane region of British Columbia along a plateau stretching from the Fraser Canyon to the Cariboo Mountains. The name is a reference to the woodland caribou that were once abundant in the region...

 region of the Central Interior of British Columbia

British Columbia Interior

The British Columbia Interior or BC Interior or Interior of British Columbia, usually referred to only as the Interior, is one of the three main regions of the Canadian province of British Columbia, the other two being the Lower Mainland, which comprises the overlapping areas of Greater Vancouver...

, Canada

Canada

Canada is a North American country consisting of ten provinces and three territories. Located in the northern part of the continent, it extends from the Atlantic Ocean in the east to the Pacific Ocean in the west, and northward into the Arctic Ocean...

. Located on 105 Mile Lake, it is between Lac La Hache and the town of 100 Mile House. Like other milehouse-names in this region its name is derived from its distance from Lillooet

Lillooet, British Columbia

Lillooet is a community on the Fraser River in western Canada, about up the British Columbia Railway line from Vancouver. Situated at an intersection of deep gorges in the lee of the Coast Mountains, it has a dry climate- of precipitation is recorded annually at the town's weather station,...

 via the Old Cariboo Road

Old Cariboo Road

The Old Cariboo Road is a reference to the original wagon road to the Cariboo gold fields in what is now the Canadian province of British Columbia...

.

105 Mile House should not be confused with 105 Mile Post Indian Reserve No. 2, which is near Ashcroft to the south.