AM-905
Encyclopedia
AM-905 is an analgesic
drug which is a cannabinoid agonist
with a conformationally restricted side chain. It is a potent and reasonably selective agonist for the CB1 cannabinoid receptor
, with a Ki
of 1.2nM at CB1 and 5.3nM at CB2.
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
drug which is a cannabinoid agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
with a conformationally restricted side chain. It is a potent and reasonably selective agonist for the CB1 cannabinoid receptor
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
, with a Ki
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant is a specific type of equilibrium constant that measures the propensity of a larger object to separate reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into...
of 1.2nM at CB1 and 5.3nM at CB2.