ARHGEF7
Encyclopedia
Rho guanine nucleotide exchange factor 7 is a protein
that in humans is encoded by the ARHGEF7 gene
.
with GIT1
, SHANK3
, Cbl gene
, SHANK1
and SHANK2
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the ARHGEF7 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
ARHGEF7 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with GIT1
GIT1
ARF GTPase-activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene.GIT1 contains an ARFGAP domain, Anykrin repeats, and a GRK-interacting domain. The Arf-GAP domain, which enables it to act as a GTPase activating protein for the Arf family of GTPases, has been shown to be...
, SHANK3
SHANK3
SH3 and multiple ankyrin repeat domains 3, also known as SHANK3, is a human gene on chromosome 22.This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane...
, Cbl gene
Cbl gene
Cbl is a mammalian gene encoding several proteins including E3 ubiquitin-protein ligase CBL involved in cell signalling and protein ubiquitination...
, SHANK1
SHANK1
SH3 and multiple ankyrin repeat domains protein 1 is a protein that in humans is encoded by the SHANK1 gene.-Interactions:SHANK1 has been shown to interact with SPTAN1, BAIAP2, ARHGEF7, DNM2 and Somatostatin receptor 2.-Further reading:...
and SHANK2
SHANK2
SH3 and multiple ankyrin repeat domains protein 2 is a protein that in humans is encoded by the SHANK2 gene. Two alternative splice variants, encoding distinct isoforms, are reported...
.
External links
- ARHGEF7 Info with links in the Cell Migration Gateway