ATP synthase delta subunit
Encyclopedia
ATP synthase delta subunit is a subunit
of bacteria
l and chloroplast
ATPase
, or OSCP (oligomycin
sensitivity conferral protein
) in mitochondrial ATPase (note that in mitochondria there is a different delta subunit).
The OSCP/delta subunit appears to be part of the peripheral
stalk that holds the F1 complex alpha3beta3 catalytic core stationary against the torque
of the rotating central stalk, and links subunit A of the F0 complex with the F1 complex. In mitochondria, the peripheral stalk consists of OSCP, as well as F0 components F6, B and D. In bacteria and chloroplasts the peripheral stalks have different subunit compositions: delta and two copies of F0 component B (bacteria), or delta and F0 components B and B (chloroplasts).
Human delta subunit of ATP synthase is coded by gene
ATP5O
.
Subunit
A subunit is a subdivision of a larger unit.*In military organizations, a sub-unit is smaller in size than a battalion and is commanded by an Officer Commanding.*In chemistry, the term can refer to a monomer...
of bacteria
Bacteria
Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...
l and chloroplast
Chloroplast
Chloroplasts are organelles found in plant cells and other eukaryotic organisms that conduct photosynthesis. Chloroplasts capture light energy to conserve free energy in the form of ATP and reduce NADP to NADPH through a complex set of processes called photosynthesis.Chloroplasts are green...
ATPase
ATPase
ATPases are a class of enzymes that catalyze the decomposition of adenosine triphosphate into adenosine diphosphate and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme harnesses to drive other chemical reactions that would not otherwise occur...
, or OSCP (oligomycin
Oligomycin
Oligomycins are macrolides created by Streptomyces that can be poisonous to other organisms.-Function:They have use as antibiotics.In addition, oligomycin inhibits ATP synthase by blocking its proton channel , which is necessary for oxidative phosphorylation of ADP to ATP . The inhibition of ATP...
sensitivity conferral protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
) in mitochondrial ATPase (note that in mitochondria there is a different delta subunit).
The OSCP/delta subunit appears to be part of the peripheral
Peripheral
A peripheral is a device attached to a host computer, but not part of it, and is more or less dependent on the host. It expands the host's capabilities, but does not form part of the core computer architecture....
stalk that holds the F1 complex alpha3beta3 catalytic core stationary against the torque
Torque
Torque, moment or moment of force , is the tendency of a force to rotate an object about an axis, fulcrum, or pivot. Just as a force is a push or a pull, a torque can be thought of as a twist....
of the rotating central stalk, and links subunit A of the F0 complex with the F1 complex. In mitochondria, the peripheral stalk consists of OSCP, as well as F0 components F6, B and D. In bacteria and chloroplasts the peripheral stalks have different subunit compositions: delta and two copies of F0 component B (bacteria), or delta and F0 components B and B (chloroplasts).
Human delta subunit of ATP synthase is coded by gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
ATP5O
ATP5O
ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ATP5O gene.-Further reading:...
.
Further reading
- [1]. Structure and arrangement of the delta subunit in the E. coli ATP synthase (ECF1F0). Wilkens S, Rodgers A, Ogilvie I, Capaldi RA; Biophys Chem 1997;68:95-102.