Aminoquinoline
Encyclopedia
Quinoline
Quinoline is a heterocyclic aromatic organic compound. It has the formula C9H7N and is a colourless hygroscopic liquid with a strong odour. Aged samples, if exposed to light, become yellow and later brown...
, most notable for their roles as antimalarial drug
Antimalarial drug
Antimalarial medications, also known as antimalarials, are designed to prevent or cure malaria. Such drugs may be used for some or all of the following:* Treatment of malaria in individuals with suspected or confirmed infection...
s.
Depending upon the location of the amino group, they can be divided into:
- 4-Aminoquinoline4-Aminoquinoline4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline.A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine....
- 8-Aminoquinoline8-Aminoquinoline8-Aminoquinoline is a form of aminoquinoline with an amine at the 8-position of quinoline.The 8-aminoquinoline family of drugs contains three members, primaquine, tafenoquine and pamaquine and are used in the treatment of malaria...