Apoptosis antagonizing transcription factor
Encyclopedia
Protein AATF is a protein
that in humans is encoded by the AATF gene
.
with Sp1 transcription factor, POLR2J
, PAWR
and Retinoblastoma protein
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the AATF gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
Apoptosis-antagonizing transcription factor has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Sp1 transcription factor, POLR2J
POLR2J
DNA-directed RNA polymerase II subunit RPB11-a is an enzyme that in humans is encoded by the POLR2J gene.-Interactions:POLR2J has been shown to interact with POLR2C, SATB1 and Apoptosis antagonizing transcription factor.-Further reading:...
, PAWR
PAWR
PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 , is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells....
and Retinoblastoma protein
Retinoblastoma protein
The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in the majority types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide...
.