Bacteroides melaninogenicus
Encyclopedia
Bacteroides melaninogenicus is a normal flora found in the upper respiratory tract
Upper respiratory tract
The upper respiratory tract or upper airway primarily refers to the parts of the respiratory system lying outside of the thorax or above the sternal angle. Another definition commomly used in medicine is the airway above the glottis or vocal cords...

. it is an important human pathogen in various anaerobic infection
Anaerobic infection
Anaerobic infections are caused by anaerobic bacteria. Anaerobic bacteria do not grow on solid media in room air ; facultative anaerobic bacteria can grow in the presence as well as in the absence of air. Microaerophilic bacteria do not grow at all aerobically or grow poorly, but grow better under...

s often mixed with other aerobic and anaerobic bacteria.

The name Bacteroides melaninogenicus was later changed to Prevotela melaninogenica. Steroids may facilitate growth.

Prevotella spp. are part of the normal human oral and vaginal flora and are the predominant anaerobic gram negative bacilli recovered from anaerobic infection
Anaerobic infection
Anaerobic infections are caused by anaerobic bacteria. Anaerobic bacteria do not grow on solid media in room air ; facultative anaerobic bacteria can grow in the presence as well as in the absence of air. Microaerophilic bacteria do not grow at all aerobically or grow poorly, but grow better under...

s of the respiratory tract. These include aspiration pneumonia, lung abscess, and chronic otitis media and sinusitis. They have been recovered also from abscesses and burns around the oral cavity, human bites, paronychia
Paronychia
The nail disease paronychia , commonly misidentified as a synonym for whitlow or felon, is an often-tender bacterial or fungal hand infection or foot infection where the nail and skin meet at the side or the base of a finger or toenail...

, urinary tract infection
Urinary tract infection
A urinary tract infection is a bacterial infection that affects any part of the urinary tract. Symptoms include frequent feeling and/or need to urinate, pain during urination, and cloudy urine. The main causal agent is Escherichia coli...

, brain abscesses, osteomyelitis
Osteomyelitis
Osteomyelitis simply means an infection of the bone or bone marrow...

 and bacteremia
Bacteremia
Bacteremia is the presence of bacteria in the blood. The blood is normally a sterile environment, so the detection of bacteria in the blood is always abnormal....

 associated with upper respiratory tract infections. Prevotella spp. play a major role in the pathogenesis of periodontal disease and periodontal abscesses. There will be high prevalence of Prevotela melaninogenics in the dental plaque
Dental plaque
Dental plaque is a biofilm, usually a pale yellow, that develops naturally on the teeth. Like any biofilm, dental plaque is formed by colonizing bacteria trying to attach themselves to a smooth surface...

 of person with Down's syndrome.
This bacteria synthesizes collagenase in periodontal disease
Periodontal disease
Periodontitis is a set of inflammatory diseases affecting the periodontium, i.e., the tissues that surround and support the teeth. Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth...

.
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