Benzomorphan
Encyclopedia
Benzomorphan is a chemical compound
.
It is the base for a series of drug
s which variably act on the opioid
and sigma receptor
s, including, but not limited to, the following compounds:
Some of these agents are used as analgesic
s, including pentazocine
, phenazocine
, dezocine
, and eptazocine
.
Chemical compound
A chemical compound is a pure chemical substance consisting of two or more different chemical elements that can be separated into simpler substances by chemical reactions. Chemical compounds have a unique and defined chemical structure; they consist of a fixed ratio of atoms that are held together...
.
It is the base for a series of drug
Drug
A drug, broadly speaking, is any substance that, when absorbed into the body of a living organism, alters normal bodily function. There is no single, precise definition, as there are different meanings in drug control law, government regulations, medicine, and colloquial usage.In pharmacology, a...
s which variably act on the opioid
Opioid
An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract...
and sigma receptor
Sigma receptor
The sigma receptors σ1 and σ2 bind to ligands such as 4-PPBP, SA 4503, ditolylguanidine, dimethyltryptamine and siramesine.- Classification :...
s, including, but not limited to, the following compounds:
Some of these agents are used as analgesic
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
s, including pentazocine
Pentazocine
Pentazocine is a synthetically prepared prototypical mixed agonist-antagonist narcotic drug of the benzomorphan class of opioids used to treat moderate to moderately severe pain...
, phenazocine
Phenazocine
Phenazocine is an opioid analgesic drug, which is related to pentazocine and has a similar profile of effects....
, dezocine
Dezocine
Dezocine was developed by American Home Products and is an opioid analgesic related to pentazocine, with a similar profile of effects that include analgesic action and euphoria at low doses, but produces dysphoria and hallucinations at high doses, most likely due to action at κ-opioid...
, and eptazocine
Eptazocine
Eptazocine is an opioid analgesic of the benzomorphan family which was introduced in Japan by Morishita in 1987. It acts as a mixed κ-opioid receptor agonist and μ-opioid receptor antagonist....
.