CVS (enzyme)
Encyclopedia
CVS is a terpene cyclase
enzyme
responsible for the biosynthesis of valencene
, a sesquiterpene
, using farnesyl pyrophosphate
as its substrate. The first CVS enzyme was isolated using orange
cDNA.
Cyclase
A cyclase is an enzyme, almost always a lyase, that catalyzes a chemical reaction to form a cyclic compound. Important cyclase enzymes include:* Adenylyl cyclase, which forms cyclic AMP from adenosine triphosphate...
enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
responsible for the biosynthesis of valencene
Valencene
Valencene is a sesquiterpene that is an aroma component of citrus fruit and citrus-derived odorants. It is cheaply obtained from Valencia oranges. Valencene is biosynthesized from FPP by the CVS enzyme....
, a sesquiterpene
Sesquiterpene
Sesquiterpenes are a class of terpenes that consist of three isoprene units and have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be acyclic or contain rings, including many unique combinations...
, using farnesyl pyrophosphate
Farnesyl pyrophosphate
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway used by organisms in the biosynthesis of terpenes, terpenoids, and sterols...
as its substrate. The first CVS enzyme was isolated using orange
Orange (fruit)
An orange—specifically, the sweet orange—is the citrus Citrus × sinensis and its fruit. It is the most commonly grown tree fruit in the world....
cDNA.