Calcinosis
Encyclopedia
Dystrophic calcification
The most common type of calcinosis is dystrophic calcificationDystrophic calcification
Dystrophic Calcification is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, including as a consequence of medical device implantation.Dystrophic calcification can...
. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices.
Metastatic calcification
Metastatic calcificationMetastatic calcification
Metastatic calcification is deposition of calcium salts in otherwise normal tissue, because of elevated serum levels of calcium in blood, which can occur because of deranged metabolism as well as increased absorption or decreased excretion of calcium and related minerals.It occurs as opposed to...
involves a systemic calcium excess imbalance, which can be caused by hypercalcemia, renal failure
Renal failure
Renal failure or kidney failure describes a medical condition in which the kidneys fail to adequately filter toxins and waste products from the blood...
, milk-alkali syndrome
Milk-alkali syndrome
In medicine, milk-alkali syndrome, also called Burnett's syndrome in honour of Charles Hoyt Burnett, the American physician who first described it, is characterized by hypercalcemia caused by repeated ingestion of calcium and absorbable alkali...
, lack or excess of other minerals, or other etiologies.
Tumoral calcinosis
The etiologyEtiology
Etiology is the study of causation, or origination. The word is derived from the Greek , aitiologia, "giving a reason for" ....
of the rare condition of tumoral calcinosis
Tumoral calcinosis
Tumoral calcinosis is a skin condition characterized by calcification of a pre-existing skin tumor ; it presents as large subcutaneous masses. The original tumor may or may not disappear leaving behind a calcified nodule that may eventually ossify ....
is not entirely understood. It is generally characterized by large, globular calcifications near joints.
See also
- calcinosis cutisCalcinosis cutisCalcinosis cutis is a type of calcinosis wherein calcium deposits form in the skin. A variety of factors can result in this condition. The most common source is dystrophic calcification, which occurs in soft tissue as a response to injury...
- dermatomyositisDermatomyositisDermatomyositis is a connective-tissue disease related to polymyositis and Bramaticosis that is characterized by inflammation of the muscles and the skin.- Causes :...
- hypercalcemia
- hyperphosphatemiaHyperphosphatemiaHyperphosphatemia is an electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood. Often, calcium levels are lowered due to precipitation of phosphate with the calcium in tissues.-Signs and symptoms:...
- sclerodermaSclerodermaSystemic sclerosis or systemic scleroderma is a systemic autoimmune disease or systemic connective tissue disease that is a subtype of scleroderma.-Skin symptoms:...
- Fahr's syndromeFahr's syndromeIdiopathic Basal Ganglia Calcification, also known as Fahr disease or Fahr’s Syndrome is a rare, genetically dominant, inherited neurological disorder characterized by abnormal deposits of calcium in areas of the brain that control movement, including the basal ganglia and the cerebral cortex...
- Primrose syndromePrimrose syndromePrimrose syndrome is a rare, slowly progressive genetic disorder that can vary symptomatically between individual cases, but is generally characterised by ossification of the external ears, learning difficulties, and facial abnormalities. It was first described in 1982 in Scotland's Royal National...