Calcinosis cutis
Encyclopedia
Calcinosis cutis is a type of calcinosis
wherein calcium deposits form in the skin. A variety of factors can result in this condition. The most common source is dystrophic calcification
, which occurs in soft tissue as a response to injury. In dogs, calcinosis cutis is virtually pathognomonic for Canine Cushing's syndrome
.
Calcinosis
-Dystrophic calcification:The most common type of calcinosis is dystrophic calcification. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices.-Metastatic calcification:...
wherein calcium deposits form in the skin. A variety of factors can result in this condition. The most common source is dystrophic calcification
Dystrophic calcification
Dystrophic Calcification is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, including as a consequence of medical device implantation.Dystrophic calcification can...
, which occurs in soft tissue as a response to injury. In dogs, calcinosis cutis is virtually pathognomonic for Canine Cushing's syndrome
Cushing's syndrome
Cushing's syndrome is a hormone disorder caused by high levels of cortisol in the blood. This can be caused by taking glucocorticoid drugs, or by tumors that produce cortisol or adrenocorticotropic hormone or CRH...
.
Types
Calcinosis cutis may be divided into the following types:- Dystrophic calcinosis cutisDystrophic calcinosis cutisDystrophic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus, and occurs in a preexisting skin lesion of inflammatory process....
- Metastatic calcinosis cutisMetastatic calcinosis cutisMetastatic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus, and associated with an internal malignancy....
- Iatrogenic calcinosis cutisIatrogenic calcinosis cutisIatrogenic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus inadvertently introduced by a medical procedure....
- Traumatic calcinosis cutisTraumatic calcinosis cutisTraumatic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus often resulting from occupational exposure, as in cases reported in oil-field workers and coal miners....
- Idiopathic scrotal calcinosisIdiopathic scrotal calcinosisIdiopathic scrotal calcinosis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus occurring on the scrotum....
- Subepidermal calcified noduleSubepidermal calcified noduleSubepidermal calcified nodule is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus, occurring most frequently as one or a few skin lesions on the scalp or face of children....
- Tumoral calcinosisTumoral calcinosisTumoral calcinosis is a skin condition characterized by calcification of a pre-existing skin tumor ; it presents as large subcutaneous masses. The original tumor may or may not disappear leaving behind a calcified nodule that may eventually ossify ....
- Osteoma cutisOsteoma cutisOsteoma cutis is a cutaneous condition characterized by the presence of bone within the skin in the absence of a preexisting or associated lesion....
Causes
Calcinosis may be the results of a variety of causes such as:- Trauma to the region
- Inflammation (bug bites, acne)
- Varicose veinsVaricose veinsVaricose veins are veins that have become enlarged and tortuous. The term commonly refers to the veins on the leg, although varicose veins can occur elsewhere. Veins have leaflet valves to prevent blood from flowing backwards . Leg muscles pump the veins to return blood to the heart, against the...
- Infections
- Tumors (malignant or benign)
- Diseases of connective tissue
- Hypercalcemia
- HyperphosphatemiaHyperphosphatemiaHyperphosphatemia is an electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood. Often, calcium levels are lowered due to precipitation of phosphate with the calcium in tissues.-Signs and symptoms:...
External links
- http://tray.dermatology.uiowa.edu/CalCut01.htm