Calcium citrate malate
Encyclopedia
Calcium citrate malate is a water-soluble calcium supplement
. It is the calcium salt of citric acid
and malic acid
with variable composition. It is purported to be highly bioavailable.
Calcium citrate malate's bioavailability stems from its water-solubility and its method of dissolution. When dissolved, it releases calcium ions and a calcium-citrate
complex. Calcium ions are absorbed directly into intestinal cells, and the citrate complex enters the body through paracellular absorption.
Calcium citrate malate is similar to calcium malate
and other calcium salts. An analysis of 15 randomized trials concluded that calcium citrate was absorbed 22% to 27% better than calcium carbonate, whether taken on an empty stomach or with food.
Dietary supplement
A dietary supplement, also known as food supplement or nutritional supplement, is a preparation intended to supplement the diet and provide nutrients, such as vitamins, minerals, fiber, fatty acids, or amino acids, that may be missing or may not be consumed in sufficient quantities in a person's diet...
. It is the calcium salt of citric acid
Citric acid
Citric acid is a weak organic acid. It is a natural preservative/conservative and is also used to add an acidic, or sour, taste to foods and soft drinks...
and malic acid
Malic acid
Malic acid is an organic compound with the formula HO2CCH2CHOHCO2H. It is a dicarboxylic acid which is made by all living organisms, contributes to the pleasantly sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms , though only the L-isomer exists...
with variable composition. It is purported to be highly bioavailable.
Calcium citrate malate's bioavailability stems from its water-solubility and its method of dissolution. When dissolved, it releases calcium ions and a calcium-citrate
Calcium citrate
Calcium citrate is the calcium salt of citric acid. It is commonly used as a food additive , usually as a preservative, but sometimes for flavor. In this sense, it is similar to sodium citrate. Calcium citrate is also used as a water softener because the citrate ions can chelate unwanted metal...
complex. Calcium ions are absorbed directly into intestinal cells, and the citrate complex enters the body through paracellular absorption.
Calcium citrate malate is similar to calcium malate
Calcium malate
Calcium malate is a compound with formula Ca. It is the calcium salt of malic acid. As a food additive, it has the E number E352.It is related to, but different from, calcium citrate malate....
and other calcium salts. An analysis of 15 randomized trials concluded that calcium citrate was absorbed 22% to 27% better than calcium carbonate, whether taken on an empty stomach or with food.