Coomassie
Overview
Triphenylmethane
Triphenylmethane, or triphenyl methane, is the hydrocarbon with the formula 3CH. This colorless solid is soluble in nonpolar organic solvents and not in water. Triphenylmethane has the basic skeleton of many synthetic dyes called triarylmethane dyes, many of them are pH indicators, and some display...
dyes that were developed for use in the textile industry but are now commonly used for staining proteins in analytical biochemistry. Coomassie Brilliant Blue G-250 differs from Coomassie Brilliant Blue R-250 by the addition of two methyl group
Methyl group
Methyl group is a functional group derived from methane, containing one carbon atom bonded to three hydrogen atoms —CH3. The group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. The methyl group can be found in three forms: anion, cation and radical. The anion...
s. The name "Coomassie" is a registered trademark of Imperial Chemical Industries
Imperial Chemical Industries
Imperial Chemical Industries was a British chemical company, taken over by AkzoNobel, a Dutch conglomerate, one of the largest chemical producers in the world. In its heyday, ICI was the largest manufacturing company in the British Empire, and commonly regarded as a "bellwether of the British...
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The name Coomassie was adopted at the end of the 19th century as a trade name by the Blackley
Blackley
Blackley is an area of the city of Manchester, in Greater Manchester, England. It is north of Manchester city centre, by a meander of the River Irk. Further north is Middleton...
based dye manufacturer Levinstein Ltd, in marketing a range of acid wool dyes
Acid dye
An acid dye is a dye, in chemical regard a sodium salt of a sulfonic, carboxylic or phenol organic acid. Acid dye is soluble in water and possesses affinity for amphoteric fibers while lacking direct dyes' affinity for cellulose fibers. When dyeing, ionic bonding with fiber cationic sites accounts...
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