Cyclazocine is a mixed opioid

Opioid

An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract...

 agonist

Agonist

An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...

/antagonist

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that does not provoke a biological response itself upon binding to a receptor, but blocks or dampens agonist-mediated responses...

 related to dezocine

Dezocine

Dezocine was developed by American Home Products and is an opioid analgesic related to pentazocine, with a similar profile of effects that include analgesic action and euphoria at low doses, but produces dysphoria and hallucinations at high doses, most likely due to action at κ-opioid...

, pentazocine

Pentazocine

Pentazocine is a synthetically prepared prototypical mixed agonist-antagonist narcotic drug of the benzomorphan class of opioids used to treat moderate to moderately severe pain...

 and phenazocine

Phenazocine

Phenazocine is an opioid analgesic drug, which is related to pentazocine and has a similar profile of effects....

. This family of opioid drugs is called the benzomorphan

Benzomorphan

Benzomorphan is a chemical compound.It is the base for a series of drugs which variably act on the opioid and sigma receptors, including, but not limited to, the following compounds:...

s or benzazocine

Benzazocine

Benzazocine, also known as benzoazocine, is a chemical compound. It consists of a benzene ring bound to an azocine ring. A related compound is benzomorphan....

s.

Use

Research into the use of cyclazocine for the treatment of bipolar

Bipolar disorder

Bipolar disorder or bipolar affective disorder, historically known as manic–depressive disorder, is a psychiatric diagnosis that describes a category of mood disorders defined by the presence of one or more episodes of abnormally elevated energy levels, cognition, and mood with or without one or...

patients with depression was undertaken by Fink and colleagues (1970). It showed that 8 out of 10 patients experienced moderate improvement.

Research during the 1960s and 1970s into the possible use of cyclazocine for management of pain, and later for assisting treatment of narcotic addiction was severely hampered by the drug's psychotomimetic, dysphoric, and hallucinatory effects.