DNase-Seq
Encyclopedia
DNase-Seq is a method in molecular biology
used to identify the location of regulatory regions, based on the genome-wide sequencing of regions super sensitivity to cleavage by DNase I. FAIRE-Seq
is a successor of DNase-Seq for the genome-wide identification of accessible DNA regions in the genome.
Molecular biology
Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry...
used to identify the location of regulatory regions, based on the genome-wide sequencing of regions super sensitivity to cleavage by DNase I. FAIRE-Seq
FAIRE-Seq
FAIRE-Seq is a method in molecular biology used for determining the sequences of those DNA regions in the genome associated with regulatory activity. In contrast to DNase-seq, the FAIRE-Seq protocol doesn't require the permeabilization of cells or isolation of nuclei, and can analyse any cell types...
is a successor of DNase-Seq for the genome-wide identification of accessible DNA regions in the genome.