Dermatitis
Encyclopedia
Etymology
Dermatitis derives from Greek derma "skin" + -itis "inflammation" and genetic disorder.Terminology
There are several different types of dermatitis. The different kinds usually have in common an allergic reactionAllergy
An Allergy is a hypersensitivity disorder of the immune system. Allergic reactions occur when a person's immune system reacts to normally harmless substances in the environment. A substance that causes a reaction is called an allergen. These reactions are acquired, predictable, and rapid...
to specific allergen
Allergen
An allergen is any substance that can cause an allergy. In technical terms, an allergen is a non-parasitic antigen capable of stimulating a type-I hypersensitivity reaction in atopic individuals....
s. The term may describe eczema
Eczema
Eczema is a form of dermatitis, or inflammation of the epidermis . In England, an estimated 5.7 million or about one in every nine people have been diagnosed with the disease by a clinician at some point in their lives.The term eczema is broadly applied to a range of persistent skin conditions...
, which is also called dermatitis eczema and eczematous dermatitis. An eczema diagnosis
Diagnosis
Diagnosis is the identification of the nature and cause of anything. Diagnosis is used in many different disciplines with variations in the use of logics, analytics, and experience to determine the cause and effect relationships...
often implies atopic dermatitis
Atopic dermatitis
Atopic dermatitis is an inflammatory, chronically relapsing, non-contagious and pruritic skin disorder...
(which is very common in children and teenagers) but, without proper context, may refer to any kind of dermatitis.
In some languages, dermatitis and eczema
Eczema
Eczema is a form of dermatitis, or inflammation of the epidermis . In England, an estimated 5.7 million or about one in every nine people have been diagnosed with the disease by a clinician at some point in their lives.The term eczema is broadly applied to a range of persistent skin conditions...
are synonyms, while in other languages dermatitis implies an acute condition and eczema a chronic one. The two conditions are often classified together.
Classification
Types of dermatitis are classified according to the cause of the condition.Contact dermatitis
Contact dermatitis
Contact dermatitis is a term for a skin reaction resulting from exposure to allergens or irritants . Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight....
is caused by an allergen or an irritating substance. Irritant contact dermatitis accounts for 80% of all cases of contact dermatitis.
Atopic dermatitis
Atopic dermatitis
Atopic dermatitis is an inflammatory, chronically relapsing, non-contagious and pruritic skin disorder...
is very common worldwide and increasing in prevalence. It affects males and females equally and accounts for 10%–20% of all referrals to dermatologists. Individuals who live in urban areas with low humidity
Humidity
Humidity is a term for the amount of water vapor in the air, and can refer to any one of several measurements of humidity. Formally, humid air is not "moist air" but a mixture of water vapor and other constituents of air, and humidity is defined in terms of the water content of this mixture,...
are more prone to develop this type of dermatitis.
Dermatitis herpetiformis
Dermatitis herpetiformis
Dermatitis herpetiformis , or Duhring's disease,Freedberg, et al. . Fitzpatrick's Dermatology in General Medicine. . McGraw-Hill. ISBN 0-07-138076-0. is a chronic blistering skin condition, characterised by blisters filled with a watery fluid...
appears as a result of a gastrointestinal condition, known as celiac disease.
Seborrheic dermatitis is more common in infants and in individuals between 30 and 70 years old. It appears to affect primarily men and it occurs in 85% of people suffering from AIDS
AIDS
Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the human immunodeficiency virus...
.
Nummular dermatitis
Nummular dermatitis
Nummular dermatitis is one of the many forms of dermatitis. Also known as discoid dermatitis, it is characterized by round or oval-shaped itchy lesions...
is a less common type of dermatitis, with no known cause and which tends to appear more frequently in middle-age people.
Stasis dermatitis
Stasis dermatitis
Stasis dermatitis refers to the skin changes that occur in the leg as a result of "stasis" or blood pooling from insufficient venous return; the alternative name of varicose eczema comes from a common cause of this being varicose veins.Insufficient venous...
is an inflammation on the lower legs which is caused by buildups of blood
Blood
Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells....
and fluid
Fluid
In physics, a fluid is a substance that continually deforms under an applied shear stress. Fluids are a subset of the phases of matter and include liquids, gases, plasmas and, to some extent, plastic solids....
and it is more likely to occur in people with varicose.
Perioral dermatitis
Perioral dermatitis
Perioral dermatitis, a condition related to acne vulgaris, consists of red papules that may appear microvesicular that typically affect the nasolabial folds , perioral area or perioccular area . It usually affects women between the ages of 20 and 45...
is somewhat similar to rosacea
Rosacea
Rosacea is a chronic condition characterized by facial erythema . Pimples are sometimes included as part of the definition. Unless it affects the eyes, it is typically a harmless cosmetic condition...
; it appears more often in women between 20 and 60 years old.
Infective dermatitis is dermatitis secondary to a skin infection
Skin infection
A skin infection is an infection of the skin. Infection of the skin is distinguished from dermatitis, which is inflammation of the skin, but a skin infection can result in skin inflammation...
Signs and symptoms
Dermatitis symptoms vary with all different forms of the condition. They range from skin rashes to bumpy rashes or including blisters. Although every type of dermatitis has different symptoms, there are certain signs that are common for all of them, including redness of the skin, swellingSwelling (medical)
In medical parlance, swelling is the transient enlargement or protuberance in the body and may include tumors. According to cause, it may be congenital, traumatic, inflammatory, neoplastic or miscellaneous....
, itching and skin lesions and sometimes oozing and scarring. Also, the area of the skin on which the symptoms appear tends to be different with every type of dermatitis.
The symptoms of contact dermatitis usually appear at the site where the allergen got into contact with the skin. Also, the symptoms of neurodermatitis are limited to a single area, often the neck
Neck
The neck is the part of the body, on many terrestrial or secondarily aquatic vertebrates, that distinguishes the head from the torso or trunk. The adjective signifying "of the neck" is cervical .-Boner anatomy: The cervical spine:The cervical portion of the human spine comprises seven boney...
, wrist
Wrist
In human anatomy, the wrist is variously defined as 1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand;...
, forearm
Forearm
-See also:*Forearm flexors*Forearm muscles...
, thigh
Thigh
In humans the thigh is the area between the pelvis and the knee. Anatomically, it is part of the lower limb.The single bone in the thigh is called the femur...
or ankle
Ankle
The ankle joint is formed where the foot and the leg meet. The ankle, or talocrural joint, is a synovial hinge joint that connects the distal ends of the tibia and fibula in the lower limb with the proximal end of the talus bone in the foot...
. More rarely, the primary symptom of this condition which is itchy skin may appear on the genital area, such as the vulva
Vulva
The vulva consists of the external genital organs of the female mammal. This article deals with the vulva of the human being, although the structures are similar for other mammals....
or scrotum
Scrotum
In some male mammals the scrotum is a dual-chambered protuberance of skin and muscle containing the testicles and divided by a septum. It is an extension of the perineum, and is located between the penis and anus. In humans and some other mammals, the base of the scrotum becomes covered with curly...
. Symptoms of this type of dermatitis may be very intense and may come and go. Irritant contact dermatitis is usually more painful than itchy.
Although the symptoms of atopic dermatitis vary from person to person, the most common symptoms are dry, itchy, red skin. Typical affected skin areas include the folds of the arms, the back of the knee
Knee
The knee joint joins the thigh with the leg and consists of two articulations: one between the fibula and tibia, and one between the femur and patella. It is the largest joint in the human body and is very complicated. The knee is a mobile trocho-ginglymus , which permits flexion and extension as...
s, wrist
Wrist
In human anatomy, the wrist is variously defined as 1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand;...
s, face
Face
The face is a central sense organ complex, for those animals that have one, normally on the ventral surface of the head, and can, depending on the definition in the human case, include the hair, forehead, eyebrow, eyelashes, eyes, nose, ears, cheeks, mouth, lips, philtrum, temple, teeth, skin, and...
and hand
Hand
A hand is a prehensile, multi-fingered extremity located at the end of an arm or forelimb of primates such as humans, chimpanzees, monkeys, and lemurs...
s. Less commonly there may be cracks behind the ears, and various other rashes on any part of the body. Itching is the primary symptoms of this condition.
Dermatitis herpetiformis symptoms include itching, stinging and a burning sensation. Papules and vesicles are commonly present. The small red bumps experienced in this type of dermatitis are usually about 1 cm in size, red in color and may be found symmetrically grouped or distributed on the upper or lower back, buttocks
Buttocks
The buttocks are two rounded portions of the anatomy, located on the posterior of the pelvic region of apes and humans, and many other bipeds or quadrupeds, and comprise a layer of fat superimposed on the gluteus maximus and gluteus medius muscles. Physiologically, the buttocks enable weight to...
, elbows, knees, neck, shoulders
Shoulders
Shoulders is drinking game that involves players competing in a fast paced game attempting to "count" to 21.-Game play:*The game begins with a player slapping his left/right shoulder, this starts the count at 1....
, and scalp
Scalp
The scalp is the anatomical area bordered by the face anteriorly and the neck to the sides and posteriorly.-Layers:It is usually described as having five layers, which can conveniently be remembered as a mnemonic:...
. Less frequently, the rash may appear inside the mouth
Mouth
The mouth is the first portion of the alimentary canal that receives food andsaliva. The oral mucosa is the mucous membrane epithelium lining the inside of the mouth....
or near the hairline.
The symptoms of seborrheic dermatitis on the other hand, tend to appear gradually, from dry or greasy scaling of the scalp (dandruff
Dandruff
Dandruff is the shedding of dead skin cells from the scalp . Dandruff is sometimes caused by frequent exposure to extreme heat and cold. As it is normal for skin cells to die and flake off, a small amount of flaking is normal and common; about 487,000 cells/cm2 get released normally after...
) to hair loss. In severe causes, pimples may appear along the hairline, behind the ears, on the eyebrows, on the bridge of the nose
Human nose
The visible part of the human nose is the protruding part of the face that bears the nostrils. The shape of the nose is determined by the ethmoid bone and the nasal septum, which consists mostly of cartilage and which separates the nostrils...
, around the nose, on the chest
Chest
The chest is a part of the anatomy of humans and various other animals. It is sometimes referred to as the thorax or the bosom.-Chest anatomy - Humans and other hominids:...
, and on the upper back. In newborns, the condition causes a thick and yellowish scalp rash, often accompanied by a diaper rash
Diaper rash
Irritant diaper dermatitis is a generic term applied to skin rashes in the diaper area that are caused by various skin disorders and/or irritants.Generic rash or irritant diaper dermatitis is characterized by joined patches of erythema and...
.
Perioral dermatitis refers to a red bumpy rash around the mouth.
Causes
A number of health conditions, allergies, genetic factors and irritantsIrritation
Irritation or exacerbation, in biology and physiology, is a state of inflammation or painful reaction to allergy or cell-lining damage. A stimulus or agent which induces the state of irritation is an irritant...
can be responsible for causing dermatitis. There are several types of dermatitis which are distinguished based on the factor that triggers the skin reaction.
Cleaning products like:
- skin soaps
- detergents
- laundry soap or
- bleachBleachBleach refers to a number of chemicals that remove color, whiten, or disinfect, often via oxidation. Common chemical bleaches include household chlorine bleach , lye, oxygen bleach , and bleaching powder...
may cause contact dermatitis.
This specific type of dermatitis can also be caused by the exposure to allergens such as:
- rubberRubberNatural rubber, also called India rubber or caoutchouc, is an elastomer that was originally derived from latex, a milky colloid produced by some plants. The plants would be ‘tapped’, that is, an incision made into the bark of the tree and the sticky, milk colored latex sap collected and refined...
, - metalMetalA metal , is an element, compound, or alloy that is a good conductor of both electricity and heat. Metals are usually malleable and shiny, that is they reflect most of incident light...
(nickel), - jewelry,
- cosmeticsCosmeticsCosmetics are substances used to enhance the appearance or odor of the human body. Cosmetics include skin-care creams, lotions, powders, perfumes, lipsticks, fingernail and toe nail polish, eye and facial makeup, towelettes, permanent waves, colored contact lenses, hair colors, hair sprays and...
, - fragrances and perfumePerfumePerfume is a mixture of fragrant essential oils and/or aroma compounds, fixatives, and solvents used to give the human body, animals, objects, and living spaces "a pleasant scent"...
, - weedsWeedA weed in a general sense is a plant that is considered by the user of the term to be a nuisance, and normally applied to unwanted plants in human-controlled settings, especially farm fields and gardens, but also lawns, parks, woods, and other areas. More specifically, the term is often used to...
(such as poison ivy) or - a common ingredient found in topical antibiotic creams: neomycinNeomycinNeomycin is an aminoglycoside antibiotic that is found in many topical medications such as creams, ointments, and eyedrops. The discovery of Neomycin dates back to 1949. It was discovered in the lab of Selman Waksman, who was later awarded the Nobel Prize in Physiology and medicine in 1951...
.
Individuals develop this condition due to a brief exposure to the allergen or to a prolonged exposure to an irritant, such as those mentioned above. Generally, people who become sensitive to an allergen will be allergic to it for the rest of their lives.
Dry skin, chronic irritation, eczema
Eczema
Eczema is a form of dermatitis, or inflammation of the epidermis . In England, an estimated 5.7 million or about one in every nine people have been diagnosed with the disease by a clinician at some point in their lives.The term eczema is broadly applied to a range of persistent skin conditions...
and psoriasis
Psoriasis
Psoriasis is an autoimmune disease that appears on the skin. It occurs when the immune system mistakes the skin cells as a pathogen, and sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis is not contagious. However, psoriasis has been linked to an increased risk of...
are possible causes of neurodermatitis.
Studies have shown that long term use of topical steroid cream, often used to treat atopic dermatitis, can make the condition much worse. Total cessation of the use of topical steroid cream can lead to cure, although there is a period of severe 'rebound' between the cessation of the use of topical steroid cream and the cure.
Another type of dermatitis, seborrheic dermatitis is usually caused by physical stress, neurological conditions such as Parkinson's disease
Parkinson's disease
Parkinson's disease is a degenerative disorder of the central nervous system...
or by traveling. Varicose veins
Varicose veins
Varicose veins are veins that have become enlarged and tortuous. The term commonly refers to the veins on the leg, although varicose veins can occur elsewhere. Veins have leaflet valves to prevent blood from flowing backwards . Leg muscles pump the veins to return blood to the heart, against the...
and chronic conditions or infections that affect the blood flow in the legs account for potential causes of stasis dermatitis.
The cause of atopic dermatitis is not known, but the disease seems to result from a combination of genetic (hereditary) and environmental factors. Usually, an irritable skin, a poor immune system and a genetic factor are included among the causes of this condition. Although stress does not cause this type of dermatitis, it has been proven to worsen it. Not least, makeup, moisturizers
Moisturizer
Moisturizers or emollients are complex mixtures of chemical agents specially designed to make the external layers of the skin softer and more pliable, by increasing its hydration by reducing evaporation. Naturally occurring skin lipids and sterols as well as artificial or natural oils,...
, topical corticosteroids and dental products that contain fluoride
Fluoride
Fluoride is the anion F−, the reduced form of fluorine when as an ion and when bonded to another element. Both organofluorine compounds and inorganic fluorine containing compounds are called fluorides. Fluoride, like other halides, is a monovalent ion . Its compounds often have properties that are...
may cause perioral dermatitis.
Dermatitis herpetiformis is caused by a gastrointestinal condition called celiac disease. Celiac disease often results after the ingestion of aliments that contain gluten
Gluten
Gluten is a protein composite found in foods processed from wheat and related grain species, including barley and rye...
.
Treatment
Treatment of dermatitis is made accordingly with the particular cause of the disease. Creams that contain corticosteroids, wet compresses and avoiding the allergens and irritants are part of most treatment plans. For some types of dermatitis, nonsteroidal medications may help relieve signs and symptoms. And for all types of dermatitis, occasional use of over-the-counter antihistamines can reduce itching.See also
- Contact dermatitisContact dermatitisContact dermatitis is a term for a skin reaction resulting from exposure to allergens or irritants . Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight....
- Grant v The Australian Knitting MillsGrant v The Australian Knitting MillsGrant v The Australian Knitting Mills is a landmark case in consumer law from 1936. It is often used as a benchmark in legal cases, and as an example for students studying law.- The case :...
- Interdigital dermatitis in cattleInterdigital dermatitis in cattleInterdigital dermatitis in cattle is caused by the anaerobic bacterium Dichelobacter nodosus. This is also the agent of footrot in sheep, but strains appear to be different and there is no cross-infection....
- List of skin diseases
External links
- Skin Exposures and Effects National Institute for Occupational Safety and Health
- NIH/Medline