Dimethylphenylpiperazinium
Encyclopedia
Dimethylphenylpiperazinium (DMPP) is a nicotinic acetylcholine receptor
agonist
which is selective
for the ganglionic subtype
.
Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction...
agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
which is selective
Binding selectivity
Binding selectivity refers to the differing affinities with which different ligands bind to a substrate forming a complex. A selectivity coefficient is the equilibrium constant for the reaction of displacement by one ligand of another ligand in a complex with the substrate...
for the ganglionic subtype
Ganglion type nicotinic receptor
The ganglion type nicotinic receptor is a type of nicotinic acetylcholine receptor, consisting of the subunit combination 23.It is located in the autonomic ganglia, where activation yields EPSP, mainly by increased Na+ and K+ permeability....
.