Diproqualone is an analogue of methaqualone

Methaqualone

Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan...

 developed in the 1980s and marketed mainly in France and some other European countries. It has sedative

Sedative

A sedative or tranquilizer is a substance that induces sedation by reducing irritability or excitement....

, anxiolytic

Anxiolytic

An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...

, antihistamine

Antihistamine

An H1 antagonist is a histamine antagonist of the H1 receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions...

 and analgesic

Analgesic

An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....

 properties, and is used primarily for the treatment of inflammatory pain associated with osteoarthritis

Osteoarthritis

Osteoarthritis also known as degenerative arthritis or degenerative joint disease, is a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion...

 and rheumatoid arthritis

Rheumatoid arthritis

Rheumatoid arthritis is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The process produces an inflammatory response of the synovium secondary to hyperplasia of synovial cells, excess synovial fluid, and the development...

, and more rarely for treating insomnia

Insomnia

Insomnia is most often defined by an individual's report of sleeping difficulties. While the term is sometimes used in sleep literature to describe a disorder demonstrated by polysomnographic evidence of disturbed sleep, insomnia is often defined as a positive response to either of two questions:...

, anxiety

Anxiety

Anxiety is a psychological and physiological state characterized by somatic, emotional, cognitive, and behavioral components. The root meaning of the word anxiety is 'to vex or trouble'; in either presence or absence of psychological stress, anxiety can create feelings of fear, worry, uneasiness,...

 and neuralgia

Neuralgia

Neuralgia is pain in one or more nerves that occurs without stimulation of pain receptor cells. Neuralgia pain is produced by a change in neurological structure or function rather than by the excitation of pain receptors that causes nociceptive pain. Neuralgia falls into two categories: central...

.

Diproqualone is the only analogue of methaqualone that is still in widespread clinical use, due to its useful anti-inflammatory and analgesic effects in addition to the sedative and anxiolytic actions common to other drugs of this class. There are still some concerns about the potential of diproqualone for abuse and overdose, and so it is not sold as a pure drug but only as the camphosulfonate salt in combination mixtures with other medicines such as Ethenzamide

Ethenzamide

Ethenzamide is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains. It is a major ingredient in numerous cold and flu medications and many prescription analgesics....

.

See also

• Methaqualone
  Methaqualone
  Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan...
  
  
• Afloqualone
  Afloqualone
  Afloqualone is an analogue of methaqualone developed in the 1980s in Japan. It has sedative and muscle relaxant effects, and has had some clinical use, although it causes photosensitization as a side effect which can cause skin problems such as dermatitis.- See also :* Methaqualone* Diproqualone*...
  
  
• Etaqualone
  Etaqualone
  Etaqualone is an analogue of methaqualone which was developed in the 1960s and marketed mainly in France and some other European countries...
  
  
• Methylmethaqualone
  Methylmethaqualone
  Methylmethaqualone is an analogue of methaqualone which has similar sedative and hypnotic properties to its parent compound, and is around the same potency. Methylmethaqualone differs from methaqualone by 4-methylation on the phenyl ring...
  
  
• Mecloqualone
  Mecloqualone
  Mecloqualone is an analogue of methaqualone which was first made in 1960 and marketed mainly in France and some other European countries. It has sedative, hypnotic and anxiolytic properties, and was used for the treatment of insomnia...
  
  
• Mebroqualone
  Mebroqualone
  Mebroqualone is an analogue of mecloqualone which presumably has similar sedative and hypnotic properties to its parent compound. Mebroqualone differs from mecloqualone by having a bromine atom instead of a chlorine on the 3-phenyl ring...
  
  
• Cloroqualone
  Cloroqualone
  Cloroqualone is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties, and was sold either alone or in combination with other ingredients as a cough medicine...