Endo Pharmaceuticals
Encyclopedia
Endo Pharmaceuticals Inc. is an American pharmaceutical company. It was created as a result of a management buyout
from DuPont Merck in 1997. Three DuPont Merck executives (Carol A. Ammon, Chairman, President & CEO, and Mariann T. MacDonald, Executive Vice President, Operations, along with another colleague) purchased all of Endo Laboratories L.L.C.'s generic products along with 12 important brand products, including Percocet
and Percodan
. The new company was called Endo Pharmaceuticals Inc.
Endo acquired Algos Pharmaceutical Corporation through a merger in July 2000 and began to trade publicly . Endo Pharmaceuticals successfully completed a secondary offering for a total of 12,925,000 shares of its common stock in Oct 2001. The net proceeds were used to pay existing bank debt.
Endo is a specialty pharmaceutical company engaged in the research, development, sale and marketing of prescription pharmaceuticals used primarily to treat and manage pain.
Endo rents some lab space from Novartis
, at the Novartis production facility in Lincoln, Nebraska. At this lab, there is quality control testing of the Endo products that are produced on-site. At this particular Novartis production site, products such as TheraFlu, Triaminic and Buckley's are produced, as well as all of the Excedrin distributed across the entire nation.
In 2009, Endo bought Indevus Pharmaceuticals to diversify into Endocrinology
and Oncology
. The company entered the male Hypogonadism
market later in 2010 with FORTESTA 2% gel.
Source:
The agreement of 6 January 2006 for Endo Pharmaceuticals to market Synera (lidocaine plus tetracaine patch) was terminated on 31 July 2008. Endo is no longer involved with the Synera patch. Zars Pharmaceuticals is the patent holder for Synera. The rights to Synera passed to Nuvo Research of Canada in May, 2011 upon the acquisition of ZARS Pharmaceuticals by Nuvo Research.
Management buyout
A management buyout is a form of acquisition where a company's existing managers acquire a large part or all of the company.- Overview :Management buyouts are similar in all major legal aspects to any other acquisition of a company...
from DuPont Merck in 1997. Three DuPont Merck executives (Carol A. Ammon, Chairman, President & CEO, and Mariann T. MacDonald, Executive Vice President, Operations, along with another colleague) purchased all of Endo Laboratories L.L.C.'s generic products along with 12 important brand products, including Percocet
Percocet
The combination oxycodone/paracetamol is a narcotic pain reliever used to treat moderate to severe acute pain, marketed by Endo Pharmaceuticals.-History:The U.S...
and Percodan
Percodan
Percodan is a drug marketed by Endo Pharmaceuticals. It is a tablet containing a mixture of 325 mg of aspirin and 4.8355 mg of oxycodone HCl . It is used to treat moderate to severe pain...
. The new company was called Endo Pharmaceuticals Inc.
Endo acquired Algos Pharmaceutical Corporation through a merger in July 2000 and began to trade publicly . Endo Pharmaceuticals successfully completed a secondary offering for a total of 12,925,000 shares of its common stock in Oct 2001. The net proceeds were used to pay existing bank debt.
Endo is a specialty pharmaceutical company engaged in the research, development, sale and marketing of prescription pharmaceuticals used primarily to treat and manage pain.
Endo rents some lab space from Novartis
Novartis
Novartis International AG is a multinational pharmaceutical company based in Basel, Switzerland, ranking number three in sales among the world-wide industry...
, at the Novartis production facility in Lincoln, Nebraska. At this lab, there is quality control testing of the Endo products that are produced on-site. At this particular Novartis production site, products such as TheraFlu, Triaminic and Buckley's are produced, as well as all of the Excedrin distributed across the entire nation.
In 2009, Endo bought Indevus Pharmaceuticals to diversify into Endocrinology
Endocrinology
Endocrinology is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions called hormones, the integration of developmental events such as proliferation, growth, and differentiation and the coordination of...
and Oncology
Oncology
Oncology is a branch of medicine that deals with cancer...
. The company entered the male Hypogonadism
Hypogonadism
Hypogonadism is a medical term for decreased functional activity of the gonads. Low testosterone is caused by a decline or deficiency in gonadal production of testosterone in males...
market later in 2010 with FORTESTA 2% gel.
Personnel
- Chief executive officerChief executive officerA chief executive officer , managing director , Executive Director for non-profit organizations, or chief executive is the highest-ranking corporate officer or administrator in charge of total management of an organization...
: David P. Holveck (as of April 2008) - Chief financial officerChief financial officerThe chief financial officer or Chief financial and operating officer is a corporate officer primarily responsible for managing the financial risks of the corporation. This officer is also responsible for financial planning and record-keeping, as well as financial reporting to higher management...
: Charles A. Rowland Jr. (Resigned Sept 2008) - The company's sales force numbers 690
Products
- AmantadineAmantadineAmantadine is the organic compound known formally as 1-adamantylamine or 1-aminoadamantane. The molecule consists of adamantane backbone that has an amino group substituted at one of the four methyne positions. This pharmaceutical is sold under the name Symmetrel for use both as an antiviral and an...
(Symmetrel) - CarbidopaCarbidopaCarbidopa is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa.- Pharmacology :...
with levodopaLevodopaL-DOPA is a chemical that is made and used as part of the normal biology of some animals and plants. Some animals including humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine , and epinephrine collectively...
(Carbidopa/Levodopa USP) - FrovatriptanFrovatriptanFrovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches and for short term prevention of menstrual migraine. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.-Pharmacology:Frovatriptan inhibits excessive dilation of...
(Frova) - HydrocodoneHydrocodoneHydrocodone or dihydrocodeinone is a semi-synthetic opioid derived from either of two naturally occurring opiates: codeine and thebaine. It is an orally active narcotic analgesic and antitussive...
with acetaminophenParacetamolParacetamol INN , or acetaminophen USAN , is a widely used over-the-counter analgesic and antipyretic . It is commonly used for the relief of headaches and other minor aches and pains and is a major ingredient in numerous cold and flu remedies...
(Zydone) - Hydrocodone with homatropineHomatropineHomatropine is an anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system...
(Hycodan) - LidocaineLidocaineLidocaine , Xylocaine, or lignocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery.- History :Lidocaine, the first amino...
(Lidoderm)- Lidocaine with tetracaineTetracaineTetracaine is a potent local anesthetic of the ester group...
(Synera)
- Lidocaine with tetracaine
- MolindoneMolindoneMolindone is a therapeutic antipsychotic, used in the treatment of schizophrenia. It works by blocking the effects of dopamine in the brain, leading to diminished psychoses...
(Moban) - OxycodoneOxycodoneOxycodone is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine , and codeine.Oxycodone oral medications are generally...
with acetaminophen (PercocetPercocetThe combination oxycodone/paracetamol is a narcotic pain reliever used to treat moderate to severe acute pain, marketed by Endo Pharmaceuticals.-History:The U.S...
, Endocet) - OxycodoneOxycodoneOxycodone is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine , and codeine.Oxycodone oral medications are generally...
with aspirinAspirinAspirin , also known as acetylsalicylic acid , is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. It was discovered by Arthur Eichengrun, a chemist with the German company Bayer...
(PercodanPercodanPercodan is a drug marketed by Endo Pharmaceuticals. It is a tablet containing a mixture of 325 mg of aspirin and 4.8355 mg of oxycodone HCl . It is used to treat moderate to severe pain...
) - OxymorphoneOxymorphoneOxymorphone or 14-Hydroxydihydromorphinone is a powerful semi-synthetic opioid analgesic first developed in Germany circa 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other countries around the same time...
(Opana)
Source:
The agreement of 6 January 2006 for Endo Pharmaceuticals to market Synera (lidocaine plus tetracaine patch) was terminated on 31 July 2008. Endo is no longer involved with the Synera patch. Zars Pharmaceuticals is the patent holder for Synera. The rights to Synera passed to Nuvo Research of Canada in May, 2011 upon the acquisition of ZARS Pharmaceuticals by Nuvo Research.