Ethylidenedioxyamphetamine (EDA) is a substituted derivative of methylenedioxyamphetamine (MDA), which was developed by David Nichols and coworkers, in the course of research to determine the bulk tolerance around the benzodioxole portion of the MDA molecule. EDA was found to produce similar effects to MDA in animals but with less than half the potency, while the isopropylidinedioxy derivative (IDA) did not substitute for MDA and instead had sedative and convulsant effects. This shows limited bulk tolerance at this position and (as with 2C-G-5) makes it likely the activity of EDA will reside primarily in one enantiomer

Enantiomer

In chemistry, an enantiomer is one of two stereoisomers that are mirror images of each other that are non-superposable , much as one's left and right hands are the same except for opposite orientation. It can be clearly understood if you try to place your hands one over the other without...

, although only the racemic mix has been studied as yet.

See also

• 5-Methyl-MDA
• DFMDA
  Difluoromethylenedioxyamphetamine
  Difluoromethylenedioxyamphetamine is a substituted derivative of methylenedioxyamphetamine , which was developed by Daniel Trachsel and coworkers, along with the corresponding fluorinated derivatives of MDMA, MDEA, BDB and MBDB, with the aim of finding a non-neurotoxic drug able to be used as a...
  
  
• EDMA
  EDMA
  3,4-Ethylenedioxy-N-methylamphetamine is an entactogen drug of the amphetamine class. It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring. EDMA was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage is listed as 150–250 mg,...
  
  
• F-2 (psychedelic)
  F-2 (psychedelic)
  F-2, or 6--5-methoxy-2-methyl-2,3-dihydrobenzofuran, is a lesser-known psychedelic drug. F-2 was first synthesized by Alexander Shulgin. In his book PiHKAL , the minimum dosage is listed as 15 mg, and the duration unknown. F-2 produces few to no effects...
  
  
• IAP