Eupatorium perfoliatum or (Common) Boneset is a common perennial plant

Perennial plant

A perennial plant or simply perennial is a plant that lives for more than two years. The term is often used to differentiate a plant from shorter lived annuals and biennials. The term is sometimes misused by commercial gardeners or horticulturalists to describe only herbaceous perennials...

 native

Indigenous (ecology)

In biogeography, a species is defined as native to a given region or ecosystem if its presence in that region is the result of only natural processes, with no human intervention. Every natural organism has its own natural range of distribution in which it is regarded as native...

 to the Eastern United States

Eastern United States

The Eastern United States, the American East, or simply the East is traditionally defined as the states east of the Mississippi River. The first two tiers of states west of the Mississippi have traditionally been considered part of the West, but can be included in the East today; usually in...

 and Canada

Canada

Canada is a North American country consisting of ten provinces and three territories. Located in the northern part of the continent, it extends from the Atlantic Ocean in the east to the Pacific Ocean in the west, and northward into the Arctic Ocean...

, with a range from Nova Scotia

Nova Scotia

Nova Scotia is one of Canada's three Maritime provinces and is the most populous province in Atlantic Canada. The name of the province is Latin for "New Scotland," but "Nova Scotia" is the recognized, English-language name of the province. The provincial capital is Halifax. Nova Scotia is the...

 to Florida

Florida

Florida is a state in the southeastern United States, located on the nation's Atlantic and Gulf coasts. It is bordered to the west by the Gulf of Mexico, to the north by Alabama and Georgia and to the east by the Atlantic Ocean. With a population of 18,801,310 as measured by the 2010 census, it...

, as well as from Louisiana

Louisiana

Louisiana is a state located in the southern region of the United States of America. Its capital is Baton Rouge and largest city is New Orleans. Louisiana is the only state in the U.S. with political subdivisions termed parishes, which are local governments equivalent to counties...

 and Texas

Texas

Texas is the second largest U.S. state by both area and population, and the largest state by area in the contiguous United States.The name, based on the Caddo word "Tejas" meaning "friends" or "allies", was applied by the Spanish to the Caddo themselves and to the region of their settlement in...

 through North Dakota

North Dakota

North Dakota is a state located in the Midwestern region of the United States of America, along the Canadian border. The state is bordered by Canada to the north, Minnesota to the east, South Dakota to the south and Montana to the west. North Dakota is the 19th-largest state by area in the U.S....

. It is also called "agueweed", "feverwort" or "sweating-plant". It was introduced to American colonists

Colony

In politics and history, a colony is a territory under the immediate political control of a state. For colonies in antiquity, city-states would often found their own colonies. Some colonies were historically countries, while others were territories without definite statehood from their inception....

 by Indians

Indigenous peoples of the Americas

The indigenous peoples of the Americas are the pre-Columbian inhabitants of North and South America, their descendants and other ethnic groups who are identified with those peoples. Indigenous peoples are known in Canada as Aboriginal peoples, and in the United States as Native Americans...

 who used the plant for breaking fevers by means of heavy sweating. It is nearly always found in low, wet areas and is often found near Phalaris arundinacea (Reed canary grass).

Description

The Eupatorium perfoliatum plant grows about 1m tall, with leaves that clasp the stems and dense clusters of white heads held above the foliage.

The leaves growing together around the stem lead to a past superstition that wrapping the leaves in bandages around splints would help mend broken bones. Boneset also had other medical uses, and was a very common remedy in the United States in the 19th century. The common name boneset apparently derives from the plant's historical use in treating dengue fever

Dengue fever

Dengue fever , also known as breakbone fever, is an infectious tropical disease caused by the dengue virus. Symptoms include fever, headache, muscle and joint pains, and a characteristic skin rash that is similar to measles...

 (which is also known as breakbone).

E. perfoliatum can form hybrids with other species of the genus Eupatorium, for example Eupatorium serotinum

Eupatorium serotinum

Eupatorium serotinum, also known as late boneset or late thoroughwort, is a fall-blooming herbaceous plant native to North America...

.

Medicinal uses

Eupatorium perfoliatum extracts are used in Europe as an immunostimulating agent for the treatment of fever and colds. These effects have not been confirmed by in vitro studies, but both animal studies and in vitro experiments with plant extracts indicate anti-inflammatory effects and antiplasmodial effects against Plasmodium falciparum

Plasmodium falciparum

Plasmodium falciparum is a protozoan parasite, one of the species of Plasmodium that cause malaria in humans. It is transmitted by the female Anopheles mosquito. Malaria caused by this species is the most dangerous form of malaria, with the highest rates of complications and mortality...

, supporting the traditional use of this plant by indigenous peoples of North America.

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